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DISORDERS ASSOCIATED WITH THE IMMUNE SYSTEM

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Type I anaphylactic 30 min IgE binds to basophils and mast cells to ... Systemic anaphylaxis or anaphylactic shock. Figure 19.1 - Overview. Type I anaphylactic ... – PowerPoint PPT presentation

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Title: DISORDERS ASSOCIATED WITH THE IMMUNE SYSTEM


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DISORDERS ASSOCIATED WITH THE IMMUNE SYSTEM
  • HYPERSENSITIVITY DISORDERS
  • - ANAPHYLACTIC REACTIONS
  • - CYTOTOXIC REACTIONS
  • - IMMUNE COMPLEX REACTIONS
  • - DELAYED TYPE CELL MEDIATED
  • IMMUNE DEFICIENCIES
  • AIDS

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Table 19.1
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TYPES OF HYPERSENSITIVITY
  • Type I anaphylactic lt30 min IgE binds to
    basophils and mast cells to release histamines
    and other reactive substances as prostaglandins
    and leukotrienes. Systemic anaphylaxis or
    anaphylactic shock

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Type I anaphylactic
Figure 19.1 - Overview
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TYPE II HYPERSENSITIVITY
  • Cytotoxic Reactions generally involve the
    activation of complement by IgM and or IgG.
    Transfusion reactions

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Table 19.2
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Figure 19.4 - Overview
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TYPE III IMMUNE COMPLEX
  • Antigen antibody complexes depositied in organs
    and cause inflammatory damage.
  • Glomerular nephritis

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TYPE IV DELAYED TYPE CELL MEDIATED
HYPERSENSITIVITY
  • Caused by a subset of T lymphocytes
  • ( TD). Causes inflammation associated with
    allergic reactions, contact dermatitis, and
    tissue transplant reactions. Instead of
    occurring within a few minutes, these reactions
    not apparent for a few days. A major factor in
    the delay is the time required for the
    participating cells to reach the site of the
    antigens.

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Table 19.4
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Figure 19.11 - Overview
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Figure 19.14 - Overview
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Figure 18.12 - Overview
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Figure 19.15
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