Welcome%20To%20The%20Centre%20for%20Applied%20Genomics

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Welcome ToThe Centre for Applied Genomics
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Quotable Quotes
"The scientist is not a person who gives the
right answers he's one who asks the right
questions.
Claude Lévi-Strauss
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This week at TCAG
Lab meeting "Explosive factors and exciting
mechanisms controlling allele preference in
imprinting and gene expression" Given by Layla
Parker-Katiraee Wednesday, Nov 14, 130 PM 14th
Floor Conference Room
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(No Transcript)
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Oligo synthesis

• up to 120 bases
• conventional modified
• free delivery to downtown Toronto

New lower prices! 40 nmole 200 nmole 1000
nmole Cost per base 0.59 0.89 1.89
Cartridge purification 15.00 15.00 30.00

17,946 oligos synthesized since January 1, 2006
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DNA Sequencing

• plasmids, PCR products
• BAC ends, other genomic clones
• mutation screening
• Solexa next-generation sequencing

146,750 reads since January 1, 2006
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Now available!
Ultra-high throughput sequencing with the
Illumina Genome Analyzer
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Biobanking

• DNA preparation
• cell line transformation
• DNA, white cell, and cell line banking
• other cells on request

7,182 cell lines handled since January 1, 2006
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Genome resources

• cDNA libraries
• genomic clone libraries
• whole-genome DNA amplification
• project support database queries,
  annotation, probe selection

5,218 clones prepared since January 1, 2006
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Genetic analysis

• TaqMan, SNaPshot, microsatellites
• Illumina GoldenGate and Infinium
• Illumina gene expression analysis
• Real time PCR (qPCR)
• Mouse genotyping and linkage analysis

gt 2.5 billion genotypes since January 1, 2006
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Microarray

• Affymetrix expression and exon arrays
• SNP GeneChips and MegAllele
• Agilent oligo arrays

Affymetrix Human SNP Array 6.0 now
available! More information and pricing is
available on our website.
4,800 arrays processed since January 1, 2006
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Statistical analysis

• study design consultation
• power analysis
• analysis of genetic, microarray, genomic copy
  number, clinical, and proteomic data

12,264 hours of project support since January 1,
2006
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Cytogenomics

• karyotyping
• FISH and sequential G-to-FISH mapping
• fluorescent probe labeling
• spectral karyotping (SKY)
• breakpoint mapping
• array-CGH

707 FISH, 1,769 probes labeled since January 1,
2006
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Enabling High Impact Research
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970 facility users worldwide (28 countries)
Argentina Australia Belgium Brazil Canada China Co
sta Rica Czech Republic England Finland France Ger
many Hong Kong India Israel
Italy Japan The Netherlands Peru Scotland Singapo
re Spain Sweden Switzerland Taiwan Turkey USA
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22 Genome Canada projects supported
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The Friendly Faces of TCAG!
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SickKids Foundation
CIHR
Canadian Genetic Diseases Network
Genome Canada / OGI
McLaughlin Centre for Molecular Medicine
CFI / Ontario