Mouthwash Dental Plaque: A Microbial Biofilm - PowerPoint PPT Presentation

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Mouthwash Dental Plaque: A Microbial Biofilm

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A: Well organized community of microorganisms protected by a ... Plaque is a form of biofilm ... Caries Research 2004;38:204-211. Enamel picture from Wikipedia. ... – PowerPoint PPT presentation

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Title: Mouthwash Dental Plaque: A Microbial Biofilm


1
MouthwashDental Plaque A Microbial Biofilm
2
Introduction
  • Introduction
  • Oral Biofilms and Plaque
  • The BIG Picture
  • Mouthwashs Fave Five

Oral Biofilms and Plaque
  • Q What is a Biofilm?
  • A Well organized community of microorganisms
    protected by a matrix, usually formed under fluid
    conditions.

2
3
Introduction
  • Introduction
  • Oral Biofilms and Plaque
  • The BIG Picture
  • Mouthwashs Fave Five

Oral Biofilms and Plaque
  • Plaque is a form of biofilm
  • Dental plaque consists of many bacterial species,
    but the most dominant are S. sanguis, and S.
    mutans.
  • Q How is plaque formed?
  • A By the WEAK attachment of these bacterial
    species to salivary glycoproteins that form on
    the surface of your teeth.

3
4
Introduction
  • Introduction
  • Oral Biofilms and Plaque
  • The BIG Picture
  • Mouthwashs Fave Five

Oral Biofilms and Plaque
  • An enzyme on the surface of S. mutans called
    glycosyl transferase, uses dietary sugars (mainly
    sucrose), and forms extracellular sticky polymers
    of glucose (AKA, plaque).

4
5
Introduction
  • Introduction
  • Oral Biofilms and Plaque
  • The BIG Picture
  • Mouthwashs Fave Five

Oral Biofilms and Plaque
  • Basic Properties of Biofilms are
  • Consists of many microcolonies
  • These microcolonies have different environments,
    and they send out nutrients, waste, and oxygen to
    each other through fluid channels
  • They love low pH environments
  • Most microorganisms in biofilms are resistant to
    antibiotics. Not good!

5
6
Introduction
  • Introduction
  • Oral Biofilms and Plaque
  • The BIG Picture
  • Mouthwashs Fave Five

Oral Biofilms and Plaque
6
7
The BIG Picture
Introduction The BIG Picture Mouthwashs Fave
Five
How do we control plaque?
  • Lets try to target what it loves!
  • Can we create a neutral environment?
  • Or better, use inhibitors of acid production?
  • EX Flouride, which increases resistance to
    enamel demineralization and promotes
    remineralization.

7
8
Mouthwashs Fave Five
Introduction The BIG Picture Mouthwashs Fave
Five
Five projects for our Fave Five
  1. A device that can produce fluorides.
  2. A device that maintains the pH of a healthy
    mouth, base production.
  3. Vary the oxygen concentration, redox agents such
    as methylene blue inhibits the growth of
    gingivitis forming bacteria.
  4. Produce the wintergreen scent, or even better,
    different smelling scents.
  5. The test dummy. Just kidding!

8
9
Sources
Introduction The BIG Picture Mouthwashs Fave
Five
  1. Overman, Pamela R. Biofilm. Journal of
    Contemporary Dental Practice Volume 1, No. 3,
    Sumer Issue 2000.
  2. Marsh, Philip D. Dental plaque as a biofilm and
    microbial community - implications for health and
    disease. BMC Oral health. 10 July 2006.
  3. Marsh, Philip D. Dental Plaque as a Microbial
    Biofilm. Caries Research 200438204-211
  4. Enamel picture from Wikipedia.

9
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