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Medical Research in UAE

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Round Table 1 - May 2, 2005. An insider's view of research capacity in the region ... Special injuries such as scapular, spinal, pelvic fractures ... – PowerPoint PPT presentation

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Title: Medical Research in UAE


1
Medical Research in UAE
  • Round Table 1 - May 2, 2005
  • How to fund basic research and
  • how to link
  • local research laboratories
  • with global centers

2
Medical Research in UAE
  • Round Table 1 - May 2, 2005
  • An insiders view of research capacity in the
    region
  • S. George Carruthers MD
  • Professor of Medicine (Clinical Pharmacology)
  • Dean, Faculty of Medicine Health Sciences
  • United Arab Emirates University
  • Al Ain, UAE

3
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4
Medical Research in UAE
  • UAE federation of emirates 1971
  • UAE University established 1976
  • Faculty of Medicine established 1986
  • first medical graduates 1993
  • first health sciences graduates 2005

5
Medical Research in UAE
  • Strengths
  • Weaknesses
  • Opportunities
  • Threats

6
Medical Research in UAE
  • Strengths
  • Young, energetic country
  • Visionary, enlightened leadership
  • Wealth a prerequisite for medical research
  • Strong desire to move from developing to
    developed nation status (including trappings of
    developed nations)
  • transitional disease status of nation offers
    research opportunities and challenges (disease of
    the third world and the developed world)

7
Medical Research in UAE
  • Strengths
  • Research intensive culture in FMHS/UAEU
  • Outstanding laboratories and equipment
  • Experienced investigators
  • Adequate internal funding UAEU and FMHS
  • Adequate external funding
  • Research priority areas linked to national needs

8
Medical Research in UAE
  • Weaknesses
  • The importance of research is not widely
    appreciated
  • UAE has no Medical Research Council or NIH
  • Research philanthropy is underdeveloped
  • Disease related support is limited
  • Big Pharma is not a player
  • Hospitals and staff have little tradition of
    research
  • Research does not bring fast returns on
    investment
  • Regional perspective on ethical issues
  • Uncertainty about intellectual property issues

9
Medical Research in UAE
  • Weaknesses
  • Data bases are inadequate
  • diabetes mellitus (Type 2)
  • cardiovascular health
  • trauma
  • cancer
  • High turnover of faculty
  • Clinical research not well developed (basic
    sciences research much stronger foundations)
  • The vital circle between basic and clinical
    sciences (bench to bedside, bedside to bench) is
    fragile

10
Medical Research in UAE
  • Opportunities
  • HH Sheikh Hamdan bin Rashid Al Maktoum Awards for
    Medical Research
  • Terry Fox Cancer Funds, Dubai and Abu Dhabi
  • UAE Red Crescent Association
  • International collaborations
  • British Council
  • Universities, e.g. USA, UK, Sweden
  • International granting agencies
  • Wellcome Foundation
  • Michael J. Fox Foundation
  • Other international granting agencies

11
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12
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13
Red Crescent
14
Medical Research in UAE
  • Threats
  • Lack of critical mass of investigators
  • Lack of infrastructure
  • Fragmentation, lack of central plan
  • Inability to complete projects
  • cultural barriers
  • turnover in faculty, staff
  • funding short-falls for mega-projects

15
Medical Research at UAEU
  • Priority Research Areas at FMHS
  • to develop medical scientists and to support
    programmes of research in the basic medical
    sciences and clinical sciences, with emphasis on
    areas of special need in the United Arab
    Emirates
  • Mission Statement of FMHS, 2001

16
Medical Research at UAEU
  • Priority Research Areas at FMHS
  • Congenital and developmental disorders
  • Cancer
  • Diabetes and cardiovascular diseases
  • Immunology and infection
  • Neurosciences
  • Trauma
  • Aging and degenerative diseases

17
Medical Research at UAEU
  • Congenital and developmental disorders
  • consanguinity common
  • high morbidity and mortality in childhood
  • thalassemia, G-6PD deficiency
  • Links to Al Maktoum Centre for Arabic Genetics,
    Dubai
  • Major research conference in Dubai 2003
  • Al-Ghazali syndrome named after Professor Lihadh
    Al-Ghazali at FMHS by Malaysian investigators in
    2004

18
Medical Research at UAEU
  • Cancer
  • Tissue bank
  • Cancer registry
  • Cell biology (anatomy, biochemistry)
  • Genetics and cancer
  • Gynecological cancer/screening
  • Psychological aspects of cancer in families
  • Cancer conference planning includes regional and
    world congresses

19
Medical Research at UAEU
  • Diabetes and cardiovascular diseases
  • Rodent models of Type 1 and Type 2 diabetes
    mellitus
  • Isolated cardiomyoctes
  • Islet cell transplantation
  • Natriuretic peptides in heart failure (clinical)
  • Cardiac remodelling (clinical)
  • Clinical investigation of Diabetes Complications
    in collaboration with UAEU Research Affairs,
    Research Triangle International and UAE Red
    Crescent Association
  • International conference in 2001, planned 2006
    in Al Ain

20
Medical Research at UAEU
  • Immunology and infection
  • Bacteriology, mycology, parasitology, virology
  • Immunology
  • Innate immunity
  • Th1/Th2 modelling
  • Epidemiology
  • Zoonoses
  • Emerging infections
  • International Conference on Emerging Infectious
    Diseases 2005, Al Ain

21
Medical Research at UAEU
  • Neurosciences
  • Neuroanatomy
  • Neurophysiology
  • Psychiatry and Clinical Psychology
  • Autonomic function and disease
  • Epilepsy modeling
  • Brain imaging
  • Toxicology
  • International conference planned in November
    2005, Al Ain

22
Medical Research at UAEU
  • Trauma
  • morbidity and mortality from Road Traffic
    Accidents
  • Seat belt use, speed
  • Cyclist safety
  • morbidity and mortality from workplace accidents
  • Trauma Registry
  • Special injuries such as scapular, spinal, pelvic
    fractures
  • Radiological assessment of trauma victims
  • Monash-UAEU Road Safety Centre in Al Ain (
    Faculties of Engineering and Medicine Health
    sciences in conjunction with GM Australia)
  • ATLS programs (American College of Surgeons)
  • FAST ultrasonography program for trauma assessment

23
Medical Research at UAEU
  • Priority Research Areas at FMHS
  • Congenital and developmental disorders
  • Cancer
  • Diabetes and cardiovascular diseases
  • Immunology and infection
  • Neurosciences
  • Trauma
  • Aging and degenerative diseases
  • www.uaeu.fmhs.ac.ae

24
Medical Research at UAEU
  • Links with Global Centers
  • They already exist
  • There is a lot of room for further development
  • Foundations of relationships need to be robust
  • Challenges in UAE include developing of true
    academic health centers and academic networks
  • Excellent medical research needs context of
    excellent patient care and education
  • Medicine for profit is unlikely to encourage
    research
  • International partnerships should be win-win
  • Global partners should demonstrate regional
    commitment

25
Medical Research at UAEU
  • Building a Superior Healthcare System
  • Superior Healthcare Systems integrate
  • Superior healthcare based on evidence and high
    standards
  • Superior education of patients and health
    professionals
  • A spirit of curiosity, together with a commitment
    to research
  • A commitment to quality improvement
  • A commitment to ongoing accreditation
  • Superior Healthcare Systems require effort!

26
Medical Research at UAEU
  • Building a Superior
  • Healthcare System
  • UAE University and the Faculty of Medicine
    Health Sciences are open to partnerships.

27
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