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Excess Fats

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High Plasma Cholesterol. Liver. Cholesterol. Fat Synthesis ... Postprandial. Oxidant Stress. Nitroglycerin. Aspirin. Diet-induced Dyslipidemias and Disease ... – PowerPoint PPT presentation

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Title: Excess Fats


1
Diet-induced Dyslipidemias and Disease
Excess Fats Food Energy
High Cytosolic Acetyl-CoA NAD(P)H
Fat Synthesis VLDL Secretion
High Plasma Triglycerides NEFA
Low n-3 fats in the diet
Cytosolic HMG-CoA
High n-6 in HUFA of tissue phospholipids
Transient Postprandial Oxidant Stress
Fast Formation
HMG-CoA Reductase
Phospholipase
n-6 Eicosanoids
Mevalonate
Statins
Aspirin
Isoprenoids
Prenylated Proteins
Inflammatory cytokines Proliferation
Nitroglycerin
Synthesis of Nitric oxide
Inflammatory Vascular Wall Plaques
Platelet Activation
Reactive oxygen species
Liver Cholesterol
High Plasma Cholesterol
Ischemia
Morbidity Mortality
??
Thrombosis
Arrhythmia
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