GI Pathology II, Case 4

1
GI Pathology II, Case 4

• 60-year-old woman with easy fatiguability and
  hemoglobin of 10.2 g/100ml.

2
Identify the structures
3
A Villous Adenoma B Tubular Adenoma
4
(No Transcript)
5
Tubular Adenomas
Polyp Stalk
Normal adjacent colon mucosa
Normal adjacent colon mucosa
Even on low power note the crowded, disorganized
glands of the tubular adenoma compared to the
normal underlying colonic mucosa. The cells
lining the glands of the polyp have
hyperchromatic nuclei. There is no stalk
invasion the polyps are benign
6
Describe the histologic findings
7
Goblet cells
Hyperchromatic nuclei
The glands of the tubular adenoma are lined by
goblet cells and epithelium with elongated cells
containing hyperchromatic nuclei that are
pseudostratified (atypical or dysplastic
epithelium) There is no invasion of the lamina
propria or submucosa.