We propose that membranes whose proteins and polar lipids are distributed asymmetrically in the two halves of the membrane bilayer can act as bilayer couples, i.e., the two halves can respond differently to a perturbation. This hypothesis is applied to the interactions of amphipathic drugs with human erythrocytes. It is proposed that anionic drugs intercalate mainly into the lipid in the exterior half of the bilayer, expand that layer relative to the cytoplasmic half, and thereby induce the cell to crenate, while permeable cationic drugs do the opposite and cause the cell to form cup-shapes. This differential distribution of the drugs is attributed to interactions with the phosphatidylserine that is concentrated in the cytoplasmic half of the membrane. Impermeable amphipathic drugs intercalate only into the exterior half of the bilayer, and therefore are crenators of the intact cell.
The connective tissue of oral mucosa plays an important role in health and disease. This presentation will describe all the components of the connective tissue of oral mucosa and its function and importance.
The value chain model by Michael Porter has been covered in this presentation. The value chain comprises of primary activities: inbound logistics, internal operations, outbound logistics, marketing and sales, and service. The secondary activities are: firm's infrastructure, technology development, human resource management, and procurement. The other important concepts covered in this presentation are: Vendor Managed Inventory (VMI), Mass Customization, Postponement, Third Party Logistics (3PL), and Fourth party logistics (4PL).
The origin and history of Logistics and Supply Chain Management have been discussed in brief. Logistics and supply chain management concepts have been defined clearly and the basic concepts of supply chain explained with excellent examples.
Familiarizes the EMT-B candidate with the introductory aspects of emergency medical care. Topics covered include the Emergency Medical Services system, roles and responsibilities of the EMT-B, quality improvement, and medical direction. Also includes the training module on EMS Research. Estimated teaching 1-2 hours. Meets or exceeds USDOT NHTSA 2009 EMT/EMR training requirements.
The mTOR protein is a 289-kDa serine threonine kinase that belongs to the phosphoinositide 3-kinase (PI3K)-related kinase family and is conserved throughout evolution. mTOR nucleates at least two distinct multi-protein complexes, mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2.
Calibration of Gasoline Engine in GT-Power Software Environment: Ashish Kumar IIT ISM Dhanbad is based on the internship activity carried out at KPIT Technologies Limited, Bengaluru under the guidance of Dr. Vivekananda Mukherjee and Mr. Vinodh Sreenivasan.
Food product specifically formulated to attain higher amount of nutrients or phytochemicals than would naturally occur in that food Combination of numerous ingredients to achieve a specific set of goals e.g. infant formula as designer food influencing immune system and development
All cells have the following basic structure: A thin, flexible plasma membrane surrounds the entire cell. The interior is filled with a semi-fluid material called the cytoplasm. Also inside are specialized structures called organelles and the cell’s genetic material.
the important aspects of guidelines to be followed in dental colleges and clinic during COVID-19,DO'S and DONT'S in each speciality and hoe to treat resolved COVID-19 patients?
Microcosm:"Aquifer materials placed into laboratory vessels such as test tubes or septated serum vials for measurement of microbial activity are referred to as microcosms.
• How do individuals with disabilities interact with and use the web? Understanding how assistive technologies work. • Understanding your legal requirements - Section 508, Section 504, the Americans with Disabilities Act, and other state, U.S., and international laws • Evaluating web site accessibility - automated tools, user testing, using screen readers, and understanding the Web Content Accessibility Guidelines (WCAG) 2.0
Inorganic materials – substances present in ash when food or any living organism cremated Oxygen, hydrogen, carbon and nitrogen excluded - these form organic compounds and not found in ash Building - Form part of skeleton and all soft tissues Hence, found in rigid body structures (bones) and soft body tissues (muscles) Regulatory function - associated with variety of systems: Heart beat Clotting of blood Maintenance of internal pressure of body fluids Nerve responses Transport of oxygen from lungs to tissues.
There is a need for developing entrepreneurs in engineering education. This PPTs give a method of incorporating the entrepreneurship development in the existing curricula. This process would help the instructors to incorporate the case studies and projects to motivate the students.
Many medical problems alter the nutritional needs resulting malnutrition Poor nutrition enhance the severity and course of disease 40-60% Hospitalized patients are malnourished and other may develop it after 3 weeks of their admission Altogether, it compromise the patient immune system and reduce the rate of its recovery Illness caused severe effect on nutritional status