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Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death PowerPoint PPT Presentation
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death - How can we analyze the cell cycle? ... The process requires cell permeabilisation, RNAse treatment and staining (most ... treated (right) effect on cell cycle. ...
How can we analyze the cell cycle? ... The process requires cell permeabilisation, RNAse treatment and staining (most ... treated (right) effect on cell cycle. ...
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Homologous Recombination: PowerPoint PPT Presentation
Homologous Recombination: - Homologous Recombination: Presynaptic Filaments & Brca2 Scott Morrical Dept. of Biochemistry smorrica@zoo.uvm.edu E. coli RecA Paradigm Eukaryotic Rad51
Homologous Recombination: Presynaptic Filaments & Brca2 Scott Morrical Dept. of Biochemistry smorrica@zoo.uvm.edu E. coli RecA Paradigm Eukaryotic Rad51
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Homologous Recombination: PowerPoint PPT Presentation
Homologous Recombination: - Homologous Recombination: Presynaptic Filaments & Brca2 Scott Morrical Dept. of Biochemistry smorrica@zoo.uvm.edu E. coli RecA Paradigm Eukaryotic Rad51
Homologous Recombination: Presynaptic Filaments & Brca2 Scott Morrical Dept. of Biochemistry smorrica@zoo.uvm.edu E. coli RecA Paradigm Eukaryotic Rad51
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Holliday model PowerPoint PPT Presentation
Holliday model - Rad51-dependent ectopic (interchromosomal) gene conversion in haploid cells. crossover ... Suggests some structures are assembled during replication that are ...
Rad51-dependent ectopic (interchromosomal) gene conversion in haploid cells. crossover ... Suggests some structures are assembled during replication that are ...
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Protein interactions and Pathways PowerPoint PPT Presentation
Protein interactions and Pathways - Protein interactions and Pathways Tutorial Wellcome trust summer school Jyoti Khadake Choose a protein Rad51/BRCA2 Find out the properties of protein from Uniprotkb ...
Protein interactions and Pathways Tutorial Wellcome trust summer school Jyoti Khadake Choose a protein Rad51/BRCA2 Find out the properties of protein from Uniprotkb ...
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25 and 27 September, 2006 PowerPoint PPT Presentation
25 and 27 September, 2006 - The Double-strand Break Repair model is similar, but involves two Holliday junctions. ... RecA (Rad51p) pairs homologous regions and promotes strand exchange. ...
The Double-strand Break Repair model is similar, but involves two Holliday junctions. ... RecA (Rad51p) pairs homologous regions and promotes strand exchange. ...
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AbdelRahman et al. PNAS 98: 2538 2001 PowerPoint PPT Presentation
AbdelRahman et al. PNAS 98: 2538 2001 - In vertebrates, repair of chromosome breaks is essential for life. ... 5' to 3' resection (MRX and ?) Strand invasion (RPA, Rad51 etc) ...
In vertebrates, repair of chromosome breaks is essential for life. ... 5' to 3' resection (MRX and ?) Strand invasion (RPA, Rad51 etc) ...
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Most%20UV%20lesions%20are%20repaired%20by%20Nucleotide%20Excision%20Repair%20(NER) PowerPoint PPT Presentation
Most%20UV%20lesions%20are%20repaired%20by%20Nucleotide%20Excision%20Repair%20(NER) - Most UV lesions are repaired by Nucleotide Excision Repair (NER) ... (b) ALT (alternative lengthening of telomeres) ALT. Extension telomeres by HR demonstrated yeast ...
Most UV lesions are repaired by Nucleotide Excision Repair (NER) ... (b) ALT (alternative lengthening of telomeres) ALT. Extension telomeres by HR demonstrated yeast ...
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HR=homologous recombination PowerPoint PPT Presentation
HR=homologous recombination - Title: Slide 1 Author: radivot Last modified by: radivot Created Date: 8/9/2010 12:52:52 AM Document presentation format: On-screen Show (4:3) Company
Title: Slide 1 Author: radivot Last modified by: radivot Created Date: 8/9/2010 12:52:52 AM Document presentation format: On-screen Show (4:3) Company
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Holliday Junctions and Crossover Homeostasis    Randy Hyppa and Gerry Smith  Fred Hutchinson Cancer Research Center  Seattle, USA PowerPoint PPT Presentation
Holliday Junctions and Crossover Homeostasis Randy Hyppa and Gerry Smith Fred Hutchinson Cancer Research Center Seattle, USA - ... Single Holliday junctions predominate in S. pombe meiotic DSB repair. Hotspot DSBs are usually repaired with the sister and give few crossovers per DSB.
... Single Holliday junctions predominate in S. pombe meiotic DSB repair. Hotspot DSBs are usually repaired with the sister and give few crossovers per DSB.
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Diapositive 1 PowerPoint PPT Presentation
Diapositive 1 - Title: Diapositive 1 Author: Marc Bonneu Last modified by: LSD Ghost Created Date: 8/22/2003 3:07:01 PM Document presentation format: Affichage l' cran
Title: Diapositive 1 Author: Marc Bonneu Last modified by: LSD Ghost Created Date: 8/22/2003 3:07:01 PM Document presentation format: Affichage l' cran
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Why yeast? PowerPoint PPT Presentation
Why yeast? - Human disease genes in model organisms. Human disease genes in ... Peroxisome biogenesis. Colorectal Cancer. Genome instability. Zellweger Spectrum. Zellweger ...
Human disease genes in model organisms. Human disease genes in ... Peroxisome biogenesis. Colorectal Cancer. Genome instability. Zellweger Spectrum. Zellweger ...
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An Introduction to DNA microarrays PowerPoint PPT Presentation
An Introduction to DNA microarrays - Northern Blot (Single Gene analysis) Microarray Technology (Genome Wide Experiment) ... Northern Blots. Immobilized mRNA population hybridized with labeled ...
Northern Blot (Single Gene analysis) Microarray Technology (Genome Wide Experiment) ... Northern Blots. Immobilized mRNA population hybridized with labeled ...
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FGFR PowerPoint PPT Presentation
FGFR - FGFR
FGFR
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BRCA Genes PowerPoint PPT Presentation
BRCA Genes - BRCA Genes Dallas Henson BReast CAncer Women have about a 1 in 7 chance of getting breast cancer in their lifetime. Most cancer is sporadic, about 5-10% of cases are ...
BRCA Genes Dallas Henson BReast CAncer Women have about a 1 in 7 chance of getting breast cancer in their lifetime. Most cancer is sporadic, about 5-10% of cases are ...
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Muta PowerPoint PPT Presentation
Muta - Title: Apresenta o do PowerPoint Author: ana Last modified by: ibilce Created Date: 8/25/2004 7:04:20 PM Document presentation format: Apresenta o na tela
Title: Apresenta o do PowerPoint Author: ana Last modified by: ibilce Created Date: 8/25/2004 7:04:20 PM Document presentation format: Apresenta o na tela
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PARP Inhibitors for the treatment of MPNST PowerPoint PPT Presentation
PARP Inhibitors for the treatment of MPNST - Sarcoma Research Laboratory University of Texas, MD Anderson Cancer Center PARP Inhibitors for the treatment of MPNST Christine Kivlin, Roman Belousov, Gonzalo Lopez ...
Sarcoma Research Laboratory University of Texas, MD Anderson Cancer Center PARP Inhibitors for the treatment of MPNST Christine Kivlin, Roman Belousov, Gonzalo Lopez ...
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Selection of Candidate Genes for Population Studies PowerPoint PPT Presentation
Selection of Candidate Genes for Population Studies - Selection of Candidate Genes for Population Studies Zuo-Feng Zhang, MD, PhD Epidemiology 243: Molecular Epidemiology Gene Selection for Molecular Studies Selection of ...
Selection of Candidate Genes for Population Studies Zuo-Feng Zhang, MD, PhD Epidemiology 243: Molecular Epidemiology Gene Selection for Molecular Studies Selection of ...
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Inherited Breast and Ovarian Cancer PowerPoint PPT Presentation
Inherited Breast and Ovarian Cancer - Inherited Breast and Ovarian Cancer and Modern Women HGM 2006 - Helsinki 1 June 2006 Common disease - many, individually rare alleles Second, somatic events due to ...
Inherited Breast and Ovarian Cancer and Modern Women HGM 2006 - Helsinki 1 June 2006 Common disease - many, individually rare alleles Second, somatic events due to ...
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http://goo.gl/9acqtM PowerPoint PPT Presentation
http://goo.gl/9acqtM - parp1 , 3. * .
parp1 , 3. * .
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Selection of Candidate Genes for Population Studies PowerPoint PPT Presentation
Selection of Candidate Genes for Population Studies - Selection of Candidate Genes for Population Studies Zuo-Feng Zhang, MD, PhD Epidemiology 243: Molecular Epidemiology Gene Selection for Molecular Studies Selection of ...
Selection of Candidate Genes for Population Studies Zuo-Feng Zhang, MD, PhD Epidemiology 243: Molecular Epidemiology Gene Selection for Molecular Studies Selection of ...
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DNA Repair PowerPoint PPT Presentation
DNA Repair - DNA Repair & Recombination All 3 genomes in plants constantly being damaged by UV and other forms of radiation, chemicals, and other stresses (e.g., oxidative, heat).
DNA Repair & Recombination All 3 genomes in plants constantly being damaged by UV and other forms of radiation, chemicals, and other stresses (e.g., oxidative, heat).
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Methyldirected mismatch repair in E. coli: PowerPoint PPT Presentation
Methyldirected mismatch repair in E. coli: - MutL helps to recruit MutH, which recognizes and cleaves one DNA strand (the ... example: Benzo-[a]-pyrene (one of the primary carcinogens in tar) is metabolized ...
MutL helps to recruit MutH, which recognizes and cleaves one DNA strand (the ... example: Benzo-[a]-pyrene (one of the primary carcinogens in tar) is metabolized ...
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Oxidative Damage of DNA PowerPoint PPT Presentation
Oxidative Damage of DNA - Title: Slide 1 Author: Frank Horodyski Last modified by: Allan M. Showalter Created Date: 2/26/2004 11:06:38 PM Document presentation format: On-screen Show (4:3)
Title: Slide 1 Author: Frank Horodyski Last modified by: Allan M. Showalter Created Date: 2/26/2004 11:06:38 PM Document presentation format: On-screen Show (4:3)
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Medical Student SYB PowerPoint PPT Presentation
Medical Student SYB - CXR - Soft tissue density projecting along the right heart border on the AP view. ... Adenopathy. Esophageal lesions. Diaphragmatic hernias. Duplication cysts ...
CXR - Soft tissue density projecting along the right heart border on the AP view. ... Adenopathy. Esophageal lesions. Diaphragmatic hernias. Duplication cysts ...
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MCB 7200 PowerPoint PPT Presentation
MCB 7200 - MCB 7200 Group 1 Ashley Patton Yanyang Cuo Samantha Shaw Biological Relevance Repairs double-stranded breaks Chromosome segregation during meiosis I Genetic diversity ...
MCB 7200 Group 1 Ashley Patton Yanyang Cuo Samantha Shaw Biological Relevance Repairs double-stranded breaks Chromosome segregation during meiosis I Genetic diversity ...
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Robert Bristow MD PhD FRCPC PowerPoint PPT Presentation
Robert Bristow MD PhD FRCPC - Robert Bristow MD PhD FRCPC
Robert Bristow MD PhD FRCPC
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Double strand breaks PowerPoint PPT Presentation
Double strand breaks - C-terminus alters the conformation of Artemis such that its C-terminal tail is ... Artemis can then function to trim 5' overhangs or 3' overhangs endonucleolytically ...
C-terminus alters the conformation of Artemis such that its C-terminal tail is ... Artemis can then function to trim 5' overhangs or 3' overhangs endonucleolytically ...
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CICLO CELULAR PowerPoint PPT Presentation
CICLO CELULAR - Title: ME DE CROMATINA EXTRA DA EN LA FORMA EXTENDIDA Y CONDENSADA Author: Rodolfo Last modified by: Carmen Ramos Created Date: 5/18/2004 12:04:59 AM
Title: ME DE CROMATINA EXTRA DA EN LA FORMA EXTENDIDA Y CONDENSADA Author: Rodolfo Last modified by: Carmen Ramos Created Date: 5/18/2004 12:04:59 AM
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Common Types of DNA Damage and Spontaneous Alterations PowerPoint PPT Presentation
Common Types of DNA Damage and Spontaneous Alterations - Single strand binding protein (SSB) DNA Ligase. Eucaryotic homologs of MMR genes ... Strand invasion. Conservative DNA replication ...
Single strand binding protein (SSB) DNA Ligase. Eucaryotic homologs of MMR genes ... Strand invasion. Conservative DNA replication ...
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Lecture: DNA Repair Mechanisms PowerPoint PPT Presentation
Lecture: DNA Repair Mechanisms - DNA Repair and Mutagenesis (Friedberg, Walker, Siede) Hoeijmakers, Nature 411, ... Nucleotide Excision Repair. damaged bases are removed as oligonucleotides ...
DNA Repair and Mutagenesis (Friedberg, Walker, Siede) Hoeijmakers, Nature 411, ... Nucleotide Excision Repair. damaged bases are removed as oligonucleotides ...
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Diapositive 1 PowerPoint PPT Presentation
Diapositive 1 - Mutations in the BRCA1 and BRCA2 breast cancer susceptibility genes Breast cancer in Europe 1 in 10 women will develop breast cancer during their life 430,000 new ...
Mutations in the BRCA1 and BRCA2 breast cancer susceptibility genes Breast cancer in Europe 1 in 10 women will develop breast cancer during their life 430,000 new ...
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from Cooper, 2nd ed', Fig' 530 PowerPoint PPT Presentation
from Cooper, 2nd ed', Fig' 530 - Double-strand-break Repair Model for Homologous Recombination ... insults and normal processes. DSBs can result in cell death or ...
Double-strand-break Repair Model for Homologous Recombination ... insults and normal processes. DSBs can result in cell death or ...
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DNA reparatsioon. DNA kahjustuste allikad. PowerPoint PPT Presentation
DNA reparatsioon. DNA kahjustuste allikad. - DNA reparatsioon. DNA kahjustuste allikad. DNA-d kahjustatakse pidevalt nii rakusiseste protsesside kui ka v listegurite poolt. Hinnanguliselt toimub inimese igas ...
DNA reparatsioon. DNA kahjustuste allikad. DNA-d kahjustatakse pidevalt nii rakusiseste protsesside kui ka v listegurite poolt. Hinnanguliselt toimub inimese igas ...
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(tumor suppressor genes )  PowerPoint PPT Presentation
(tumor suppressor genes ) - : ...
: ...
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Scientific Reports PowerPoint PPT Presentation
Scientific Reports - Moreover, after poly(I : C) injection, ... and IL-6) in the retina, and attenuated intravitreal release of high-mobility group box-1 (HMGB1), ...
Moreover, after poly(I : C) injection, ... and IL-6) in the retina, and attenuated intravitreal release of high-mobility group box-1 (HMGB1), ...
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Zhang, J., H. Willers, Z. Feng, J.C. Ghosh, S. Kim, D.T. Weaver, J.H. Chung, S.N. Powell, and F. Xia. 2004. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Molecular and cell biology 24: 708-718. PowerPoint PPT Presentation
Zhang, J., H. Willers, Z. Feng, J.C. Ghosh, S. Kim, D.T. Weaver, J.H. Chung, S.N. Powell, and F. Xia. 2004. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Molecular and cell biology 24: 708-718. - ... detects DNA damage ... interrupts with p53 the cell cycle when there is damage Chk2 is a kinase BRCA1 A gene located on chromosome 17 It is necessary ...
... detects DNA damage ... interrupts with p53 the cell cycle when there is damage Chk2 is a kinase BRCA1 A gene located on chromosome 17 It is necessary ...
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CHECKPOINTS PowerPoint PPT Presentation
CHECKPOINTS - Specific point(s) in the cell cycle? Operative in normal cell cycle or only ... tension release arrest caused by unattached sex chromosome in grasshopper cells ...
Specific point(s) in the cell cycle? Operative in normal cell cycle or only ... tension release arrest caused by unattached sex chromosome in grasshopper cells ...
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DNA Repair and Cancer Susceptibility: PowerPoint PPT Presentation
DNA Repair and Cancer Susceptibility: - 'UUUMMMBBB999 | PP tt 3f 333f3 33 3f3fff ff f 3 f 3f f 333f3 33 ... 333f3 33 33 3f 3 3 3 3f3fff ff f3f33ff3f 3f3f 3fff3fffff ffff f3 ff f f f ff3 ...
'UUUMMMBBB999 | PP tt 3f 333f3 33 3f3fff ff f 3 f 3f f 333f3 33 ... 333f3 33 33 3f 3 3 3 3f3fff ff f3f33ff3f 3f3f 3fff3fffff ffff f3 ff f f f ff3 ...
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Checkpoints in Mammalian Cells PowerPoint PPT Presentation
Checkpoints in Mammalian Cells - Reduction to Homozygosity in CIN vs MIN Lines. Checkpoints - A Signal Transduction Pathway ... Ataxia Talangiectasis. Cerebellar Ataxia. Talangiectasia ...
Reduction to Homozygosity in CIN vs MIN Lines. Checkpoints - A Signal Transduction Pathway ... Ataxia Talangiectasis. Cerebellar Ataxia. Talangiectasia ...
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DNA damage and repair summary PowerPoint PPT Presentation
DNA damage and repair summary - HNPCC results from mutations in genes involved in DNA mismatch repair, ... The other strand of the duplex is displaced. Double-strand break repair ...
HNPCC results from mutations in genes involved in DNA mismatch repair, ... The other strand of the duplex is displaced. Double-strand break repair ...
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Poster Discussion III PowerPoint PPT Presentation
Poster Discussion III - Poster Discussion III Robert G. Maki, MD PhD Memorial Hospital New York, NY, USA Outcomes Median follow up 41.5 months (12-118). n = 41 : Response 22 (54% ...
Poster Discussion III Robert G. Maki, MD PhD Memorial Hospital New York, NY, USA Outcomes Median follow up 41.5 months (12-118). n = 41 : Response 22 (54% ...
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LSM3241: Bioinformatics and Biocomputing  Lecture 9: Biological Pathway Simulation  Prof. Chen Yu Zong Tel: 6874-6877 Email: yzchen@cz3.nus.edu.sg http://xin.cz3.nus.edu.sg Room 07-24, level 7, SOC1, NUS PowerPoint PPT Presentation
LSM3241: Bioinformatics and Biocomputing Lecture 9: Biological Pathway Simulation Prof. Chen Yu Zong Tel: 6874-6877 Email: yzchen@cz3.nus.edu.sg http://xin.cz3.nus.edu.sg Room 07-24, level 7, SOC1, NUS - LSM3241: Bioinformatics and Biocomputing Lecture 9: Biological Pathway Simulation Prof. Chen Yu Zong Tel: 6874-6877 Email: yzchen@cz3.nus.edu.sg
LSM3241: Bioinformatics and Biocomputing Lecture 9: Biological Pathway Simulation Prof. Chen Yu Zong Tel: 6874-6877 Email: yzchen@cz3.nus.edu.sg
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Homologous Recombination at the Molecular Level PowerPoint PPT Presentation
Homologous Recombination at the Molecular Level - H.M Protein Machines. H.M in Eukaryotes. Mating-Type Switching ... Chi is the DNA sequence 5 GCTGGTGG 3'. When RecBCD encounters a Chi sequence, its function ...
H.M Protein Machines. H.M in Eukaryotes. Mating-Type Switching ... Chi is the DNA sequence 5 GCTGGTGG 3'. When RecBCD encounters a Chi sequence, its function ...
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Wie kontrolliert p53 die genom' Stabilitt PowerPoint PPT Presentation
Wie kontrolliert p53 die genom' Stabilitt - Importance of double-strand breaks ... XRCC-4 (XR-1 mutant of CHO) @Ch5. cloned and corrects dsbr and VDJ ... p53 protein plays a major role in cancer risk ...
Importance of double-strand breaks ... XRCC-4 (XR-1 mutant of CHO) @Ch5. cloned and corrects dsbr and VDJ ... p53 protein plays a major role in cancer risk ...
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GENETICA 2010 PowerPoint PPT Presentation
GENETICA 2010 - PARTE III: VARIABILIDAD DEL MATERIAL GENETICO Teorica 9 El genoma humano no soporta grandes cambios en su secuencia sin que se traduzcan en patologias.
PARTE III: VARIABILIDAD DEL MATERIAL GENETICO Teorica 9 El genoma humano no soporta grandes cambios en su secuencia sin que se traduzcan en patologias.
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DNA damage and repair and their role in carcinogenesis PowerPoint PPT Presentation
DNA damage and repair and their role in carcinogenesis - helps to stabilize p53) Homologous repair of DSBs. via recombination. Non-homologous end joining ... Nucleotide excision repair (to remove thymine-dimers after UV) ...
helps to stabilize p53) Homologous repair of DSBs. via recombination. Non-homologous end joining ... Nucleotide excision repair (to remove thymine-dimers after UV) ...
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DNA II PowerPoint PPT Presentation
DNA II - Breast Cancer gene does not make a protein needed to repair DNA ... a body of recent studies showing that BRCA2 and its related gene product BRCA1 ...
Breast Cancer gene does not make a protein needed to repair DNA ... a body of recent studies showing that BRCA2 and its related gene product BRCA1 ...
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Understanding Structural Mechanisms Of DNA Processing Assemblies PowerPoint PPT Presentation
Understanding Structural Mechanisms Of DNA Processing Assemblies - A Common Mode of Interaction for Different DNA Repair Proteins ... spectra in 40 kDa ternary complex. 15N. RPA70AB/ssDNA T-ag. RPA70AB/T-ag ssDNA ...
A Common Mode of Interaction for Different DNA Repair Proteins ... spectra in 40 kDa ternary complex. 15N. RPA70AB/ssDNA T-ag. RPA70AB/T-ag ssDNA ...
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CICLO CELULAR PowerPoint PPT Presentation
CICLO CELULAR - CICLO CELULAR MITOSIS - MEIOSIS Comparaci n entre metafase y anafase I yII -Recombinaci n gen tica -Segregaci n al azar de los hom logos en la anafase I ...
CICLO CELULAR MITOSIS - MEIOSIS Comparaci n entre metafase y anafase I yII -Recombinaci n gen tica -Segregaci n al azar de los hom logos en la anafase I ...
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TRACO PowerPoint PPT Presentation
TRACO - TRACO Kevin Camphausen, M.D. Radiation Oncology Branch NCI ...
TRACO Kevin Camphausen, M.D. Radiation Oncology Branch NCI ...
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A1261926009OXxbp PowerPoint PPT Presentation
A1261926009OXxbp - Genetic Basis of
Genetic Basis of
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Protein%20Complex%20Detection%20in%20Large%20Protein%20Interaction%20Networks PowerPoint PPT Presentation
Protein%20Complex%20Detection%20in%20Large%20Protein%20Interaction%20Networks - ... Interactive viewer for directed mode Evaluation Require interactions and known complexes Interactions from Saccharomyces ... Signal transduction 6/17 ...
... Interactive viewer for directed mode Evaluation Require interactions and known complexes Interactions from Saccharomyces ... Signal transduction 6/17 ...
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COMS 6998-06 Network Theory Week 10: April 3, 2008 PowerPoint PPT Presentation
COMS 6998-06 Network Theory Week 10: April 3, 2008 - The process of converting genetic information (DNA) into proteins ... http://www.biology.arizona.edu/biochemistry] Polypeptides ...
The process of converting genetic information (DNA) into proteins ... http://www.biology.arizona.edu/biochemistry] Polypeptides ...
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African Trypanosomes PowerPoint PPT Presentation
African Trypanosomes - African Trypanosomes
African Trypanosomes
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Hereditary cancer syndrome? PowerPoint PPT Presentation
Hereditary cancer syndrome? - 2007 ,
2007 ,
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