Nerve and Muscle Physiology

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Nerve and Muscle Physiology

• Plasma Membranes of Excitable tissues
• Ref Guyton, 12th ed pp 57-69. 11th ed p57-71,

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Fig. 12.09a,b
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Nernest equation
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Ek
E (mV) - 61.log (Ci/Co) E Equilibrium
potential for a univalent ion Ci conc. inside
the cell. Co conc. outside the cell.
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Goldman Hodgkin Katz equation
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Goldman-Hodgkin-Katz equation

• EMF (mV)
• - 61. log ( CiNa. PNa CiK. PK CoCl-
  .PCl- )
• (CoNa PNa CoK PK CiCl-
  PCl-)
• Ci Conc. inside
• Co Conc. outside
• P permeability of the membrane to that ion.

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