What happens when Meiosis Goes WRONG??

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What happens when Meiosis Goes WRONG??
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• When homologous chromosomes fail to separate it
  is called nondisjunction
• Abnormal chromosomes will make their way into
  gametes
• This may occur during Meiosis 1 or Meiosis 2
• A fetus may be naturally aborted
• A disorder may occur

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• Trisomy - three of the same number of chromosome

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• Down Syndrome
• Trisomy 21
• Three copies of the 21st chromosome
• Mild to severe Mental Retardation
• Increased susceptibility to many diseases and
  higher frequency of some birth defects

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When something goes wrong with the division of
the sex chromosome..

• Turners- only one X chromosome is inherited
• Women are sterile, Sex organs dont develop at
  puberty
• Kleinefelters syndrome
• XXY Kleinfelters small testes, man is sterile,
  female characteristics

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• Trisomy 18
• Birth defects , increase in infant mortality,
  developmental delay
• Trisomy 13
• Small head, birth size, heart defects, vision and
  hearing problems, disabilities

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Your Job

• Create a Karyotype
• Determine the diagnosis
• Downsyndrome, Klienfelters, or Turners Syndrome