Online Supplementary Figure 2. Forest plots of significant odds ratios (ORs) of childhood acute lymphoblastic leukemia associated with polymorphic variants. Boxes denote allelic OR point estimates, their areas being proportional to the inverse variance - PowerPoint PPT Presentation

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Online Supplementary Figure 2. Forest plots of significant odds ratios (ORs) of childhood acute lymphoblastic leukemia associated with polymorphic variants. Boxes denote allelic OR point estimates, their areas being proportional to the inverse variance

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Title: Online Supplementary Figure 2. Forest plots of significant odds ratios (ORs) of childhood acute lymphoblastic leukemia associated with polymorphic variants. Boxes denote allelic OR point estimates, their areas being proportional to the inverse variance


1
Online Supplementary Figure 2. Forest plots of
significant odds ratios (ORs) of childhood acute
lymphoblastic leukemia associated with
polymorphic variants. Boxes denote allelic OR
point estimates, their areas being proportional
to the inverse variance weight of the estimate.
Horizontal lines represent 95 confidence
intervals. The diamond (and broken line)
represents the summary ORs computed under a fixed
effects model, with 95 confidence interval given
by its width. The unbroken vertical line is at
the null value (OR1.0). (A) MTRR A66G, AG vs.
AA (B) MTRR A66G, GG vs. AA (C) MTRR A66G,
GGAG vs. AA (D) SHMT1 C1420T, CT vs. CC (E)
RFC1 G80A, GA vs. GG (F) RFC1 G80A, AA vs. GG
(G) RFC1 G80A, GAAA vs. GG (H) NQO1 C609T,
CTTT vs. CC (I) GSTM1, null vs. present (J)
CYP1A1 T6235C, TC vs. TT (K) CYP1A1 T6235C,
CTCC vs. TT (L) CYP2E15B, heterozygous (M)
CYP2E15B, carrier status (N) XRCC1 G28152A, GA
vs. GG (O) XRCC1 G28152A, GAAA vs. GG
2
A. MTRR A66G, AG vs. AA
3
B. MTRR A66G, GG vs. AA
4
Phet0.82
.4
1
1.7
C. MTRR A66G, GGAG vs. AA
5
D. SHMT1 C1420T, CT vs. CC
6
E. RFC1 G80A, GA vs. GG
7
F. RFC1 G80A, AA vs. GG
8
Phet0.49
G. RFC1 G80, GAAA vs. GG
9
H. NQO1 C609T, CTTT vs. CC
10
I. GSTM1, null vs. present
11
J. CYP1A1 T6235C, TC vs. TT
12
K. CYP1A1 T6235C, CTCC vs. TT
13
L. CYP2E1 5B, heterozygous
14
M. CYP2E1 5B, carrier status
15
N. XRCC1 G28152A, GA vs. GG
16
O. XRCC1 G28152A, GAAA vs. GG
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