Title: Renal Pathology II, Case 2
1Renal Pathology II,Case 2
- A 63-year-old man presents with right flank pain
that has been ongoing for the past several months
2Identify the organ Describe the gross
findings Identify the structures
3A Carcinoma B - Ureter
Renal Cell Carcinoma The surgical specimen
consists of a whole kidney and attached ureter.
There is a large, irregular carcinoma in the
superior pole of the kidney.
4Identify the organ Describe the gross
findings Identify the structures
5A Carcinoma B Normal Cortex
Renal Cell Carcinoma The surgical specimen
consists of a bisected kidney that contains a
renal cell carcinoma in the superior pole. The
large, irregular neoplasm is yellow to golden and
contains areas of hemorrhage (red). The yellow
color and hemorrhage (increased vascularity) are
characteristic pathologic findings in a renal
cell carcinoma. Correlate the pathologic change
with possible clinical presentations.
6Describe the gross findings Identify the
structures. Diagnosis?
7A Carcinoma B Normal cortex C Ureter D -
Aorta
Renal Cell Carcinoma The autopsy specimen
consists of a bisected left kidney, normal right
kidney (arrow) and attached aorta. A renal cell
carcinoma occupies the superior pole of the left
kidney. The neoplasm is yellow and contains
extensive hemorrhage
8Describe the low and high power histologic
findings of sections from the mass
Renal cell carcinoma, clear cell type Tumor cells
are rounded or polygonal shaped with abundant
clear or granular cytoplasm (on special stains
the cytoplasm stains for fat and glycogen).