Cell Cycle

1
Cell Cycle Mitosis
Chapter 6
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Cell Division

• Growth
• Development
• Reproduction
• Tissue repair

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Cell Cycle
Duplication of each chromatid
Cell contains twice as much DNA as compared to
the cell when in G1
4
The Cell Cycle

• Interphase
• First growth (G1) phase Grows rapidly, carries
  out normal functions
• Synthesis (S) phase
• Second growth (G2) phase Growth and preparation
  for mitosis
• Mitosis Nucleus is divided chromosomes
  divided
• Cytokinesis Cytoplasm divides
• The end result is 2 genetically identical
  daughter cells to parent cell

DNA is copied
5
Mitosis

• Prophase Chromosomes coil, nuclear envelope
  dissolves and spindle forms
• Metaphase Chromosome line up along equator.
• Anaphase Centromeres divide and sister
  chromatids move toward opposite poles.
• TelophaseNuclear envelope forms, chromosomes
  uncoil and cytokinesis begins.

6
Chromosomes
http//www.johnkyrk.com/chromosomestructure.html

• Chromosomes DNA and proteins-histones (beads on
  a string)
• Sister chromatids Two exact copies of DNA
• Centromere Point where chromatids are attached

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Mitosis in an Animal Cell
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Cytokinesis
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Makes decision of whether cell will divide
Kinases-enzymes involved in triggering events in
the cycle
DNA replication checked by DNA repair enzymes
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Growth Regulation Cancer
B/c cancer cells do not have anchorage dependence
they can go to other parts of the body thru the
bloodstream
Cancer-uncontrollable growth of cells
As cancer cells build up, they form tumors
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Mitosis in a Plant Cell
http//www.johnkyrk.com/mitosis.html