Advanced Physiology of Animals ANSC 3405

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Advanced Physiology of AnimalsANSC 3405
Welcome to

• Dr. John McGlone
• and others

Lectures Tue-Thur 1230-150 pm Labs Mon
300-550 pm
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Todays Outline

• Introductions
• Instructors, students and pictures
• Syllabus
• Class format (lectures and lab)
• Advice on preparing for class
• Lecture
• Principles of physiology
• Homeostasis
• Body size

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Introductions

• Dr. John McGlone
• Dr. Mhairi Sutherland
• Lindsey Hulbert, graduate student
• Students
• Name
• Where you are from
• Major
• Career Goals
• Student pictures

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Syllabus

• Objectives
• Overview of animal physiology
• history, complexity and integration of animal
  physiology research
• Pre requirements
• Ansc 2202 (Anatomy) or equivalent
• gt 3.0 GPA

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Syllabus

• Lecture format and materials
• Lectures, reading and research assignments,
  handouts, homework, quizzes and exams
• Class Website
• http//www.depts.ttu.edu/porkindustryinstitute/Ad
  vanced20Physiology/Advanced_Physiology.htm
• Print lectures prior to class for note taking

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Syllabus

• Textbook
• Most of the book will be covered
• Lab notebook
• With duplicate carbon pages to turn in

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Syllabus

• Grading Procedures
• Normal grading scale (90 A, etc.)
• Source of points
• Hour exams (3) 300 (37.5)
• Quizzes, homework, projects 100 (12.5)
• Final exam (comprehensive) 200 (25)
• Laboratory 200
  (25)
  -----------------
• Total 800
  (100)

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Syllabus

• Exams and quizzes/assignments
• 3 Exams on previous material
• Final exam comprehensive
• Assignments must be turn in on time
• 25 loss of points per late day
• Missed quizzes can only be made up with excused
  absences
• Attendance
• Mandatory for laboratory
• Lecture 2 excused absences, 20 point loss for
  each class missed unexcused
• If you will be missing more than 3 lectures, then
  you may need to reconsider taking this course

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Syllabus

• Laboratory
• Physiology/surgery laboratories
• Animal care and experiments outside of class
• Laboratory write-ups and research
• Assignment (Towards the end of the year) of a
  topic to present
• All laboratories will need to be written up
  (instructions and questions will be provided)

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Advanced Physiology of AnimalsANSC 3405

• Lecture 1

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Major Branches of Physiology and Medicine

• Cardiovascular
• Renal
• Respiratory
• Gastrointestinal
• Neuroscience
• Endocrinology
• Reproductive
• Orthopedic (Bone and Muscle)

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Major Branches of Physiology

• Comparative Physiology
• Environmental Physiology
• Evolutionary Physiology
• Developmental Physiology
• Cell Physiology/Biology

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Biological function at each level of organization
(See Figure 1.1 page 6 in text)
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Physiology is an Integrating Science

• How did a system evolve?
• What were the survival advantages for this
  feature?
• How does ontogeny reflect evolution?

Ontogeny recapitulates phylogeny
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Brief History of Physiology

• Socrates
• Aristotle
• Galileo (1568-1657)
• Marcello Malpighi (1628-1694)
• Microscopic biology/physiology
• Antoine Lavoiser (1578-1657)
• Chemistry metabolism oxygen consumption
• William Harvey (1578-1657)

470 B.C.
384 B.C.
A.D.
1500
1600
1700
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Brief History of Physiology
1800

• The rapid expansion of our modern knowledge in
  physiology began in the late 1800s
• 1920-1950s Phase of classic physiology research
• 1950-1980 Phase of biochemical discoveries DNA,
  Enzymes, Receptors, Hormones, etc.
• 1980-present Transgenics, cloning, knock-outs,
  xenotransplantation, and much more.

1900
2000
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Homeostasis

• The tendency of organisms to regulate and
  maintain relative internal stability

• Claude Bernard (1872)
• The milieu interieur
• Constancy of the internal environment is the
  condition of life
• Walter B. Cannon (1871-1945)
• Sympathetic flight or fight response
• Homeostasis

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Feedback and Control

• Negative feedback systems and loops
• Positive feedback systems and loops
• Conformers and regulators

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Negative Feedback
(Read page 11 in text)
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Positive Feedback
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Units of Measure
1012 Tera T
109 Giga G
106 Mega M
103 Kilo k
10 Hecto h
10 Deka da
10-1 Deci D
10-2 Centi c
10-3 Milli m
10-6 Micro µ
10-9 Nano n
10-12 Pico p
10-15 Femto f
10-18 atto a

• Metric System in Science
• Liquid- Liter, L
• Solid- Grams, g
• Length- Meters, m
• Molecule concentration- moles

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Converting Units

• Conversion of units is very important in any
  field

1 cc 1mL 5 mL 1 tsp 1 kg 2.2 lb35.3 oz
1 m 39.37 in3.28 ft 1m2 10.76 ft2 2.24cm
1in 3.28 ft 1m
http//www.onlineconversion.com/
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Size, volume and mass

• Smaller bodies have more mass per unit of
  surface area

• Smaller bodies exchange heat more with the
  environment than larger ones
• This concept works for cells as well as animals
  and objects

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Size, volume and mass
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Surface Area Calculations

• Area, m2 0.1 wt0.667 (wt, in kg)
• Calculate surface area for
• 1000, 30 g mice ?
• 1, 30 kg pig ?

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The End