Title: Mountain West Research Consortium Clinical Translational Research
1Mountain West Research ConsortiumClinical
Translational Research Infrastructure
NetworkThe Mountain West CTR-IN
Robert D. Langer, MD, MPH Principal
Investigator Research Professor of Allied Health
Sciences, UNLV Associate Dean for Clinical and
Translational Research and Professor of Family
Medicine-Las Vegas, UNSOM
NIGMS Award 1U54GM104944-01A1
2What is it?
- 20 million 5 year NIH Grant under the IDeA
Program - Involving 13 universities across the 7 IDeA
states in the Mountain West Research Consortium
3What are the 7 Mountain West states?
- Alaska
- Hawaii
- Idaho
- Montana
- Nevada
- New Mexico
- Wyoming
4- Support
- to foster Clinical and Translational Research
(CTR) according to NIH Definitions - for Core Resources to facilitate the development
of researchers moving into CTR - BOOTSTRAP CTR ACROSS THE MOUNTAIN WEST
5a rising tide that
We will sink or swim based on the increase in
R-level translational and clinical research
that we achieve across the region over the next 4
years
6Who is in it?
- UNLV host
- UNR/UNSOM
- U. Alaska Anchorage
- U. Alaska Fairbanks
- U. Hawaii Manoa
- Boise State U.
- Idaho State U.
- U. Idaho
- Montana State U.
- U. Montana
- New Mexico State U.
- U. New Mexico
- U. Wyoming
7What will it do?
- Provide Pilot Grants of 40,000-75,000/yr
- Support Mini-Sabbatical and Visiting Scholar
awards to build collaborations - Provide Mini-Grants for a variety of activities
that can help build independent research - Provide infrastructure and services through Key
Component Activities
8Funding preference
- Promising Early Career or New Investigators
developing clinical or translational research
programs - Established Investigators moving from bench to
translational or clinical - Projects focused on health issues relevant to the
region, including those in rural and vulnerable
populations
9What will it do?
- Use an NIH-style approach to applications and
funding - Model the processes that clinical and
translational investigators need to master to
compete successfully for NIH support
10Key Component Activities (KCAs)
- Education, Mentoring Career Development KCA
- Study Design Biostatistics KCA
- Pilot Grant KCA
- Administrative KCA, including editorial support,
award management, Annual Meeting
11- Education
- Mentoring
- Study Design
- Biostat
- Annual Meeting
ALL AVAILABLE regardless of whether youve
received a competitive award from the CTR-IN
12What will it do?
- Hold an Annual Meeting to share science,
motivate, build collaborations, conduct study
business that will - rotate across the 13 partner institutions
- feature an annual research theme relevant to
health in the region - bring together supported investigators,
interested researchers from the region, key
administrators from partners, external
scientists, the regional biostat team, and senior
project staff -
Second Annual Meeting at UNLV June 7 11,
2015 free registration, hotel rate 100/night
13Whats the current status?
- Round 1 Pilot Grants
- 24 applications, 6 awarded
- Round 1A Pilot Grants
- 63 applications, 14 awarded
- Round 2 Pilot Grants
- 97 applications, 15 awarded
14Year 1 (Rounds 11A) Pilot Grants
Round 1 Round 1A Total
Boise State 0 3 3
Idaho State 0 1 1
Montana State 2 1 3
New Mexico State 0 1 1
U Alaska - Anchorage 0 1 1
U Alaska - Fairbanks 0 1 1
U Idaho 0 1 1
U Montana 2 0 2
U Nevada Las Vegas 1 3 4
U Nevada Reno 1 1 2
U Wyoming 0 1 1
6 14 20
15Whats the current status?
- Round 2 Pilot Grant RFA for 7/1/14 6/30/15
- Process moved entirely online
- Letters of Intent with Abstacts were due 3/7/14
- 124 LOIs with Abstracts received
- Invitations to submit were provided 3/14/14
- Applications were due 4/25/14
- Awards were announced 6/26/14 via the Pilot
Grant Application Portal
16Year 2 Pilot Grant Summary
Institution LOIs Apps Awards
U. Alaska Anchorage 8 4 1
U. Alaska Fairbanks 5 5 2
Boise State U. 4 4 1
Idaho State U. 14 14 2
U. Idaho 8 4 1
Montana State U. 8 8 1
U. Montana 5 4 1
New Mexico State U. 9 8 2
UNR 23 17 2
UNLV 30 21 1
U. Wyoming 10 8 1
124 97 15
17Visiting Scholars
- Call for 02 Year open through 11/26/14
- Early Career or New Investigator status
- 8,000 to 10,000 including 10 indirect
- Investigator salary NOT allowed
- Earliest start date 03/01/15
- Funds must be expended by 06/30/15
- Applications submitted online
- Total funds available for all awards in 02 Year
40,000 - Anticipate up to 5 Awards
- Dependent on quality and budgets of applications
received - 5 Applications and 5 Awards in the 01 Year
- U Montana to PG Awardee, U Hawaii, UNLV 3
one to PG Awardee
18Mini-Sabbaticals
- One call for 02 Year -- open through 11/26/14
- Mid-Career or Established Investigator status
- Up to 20,000 including 10 indirect
- Earliest start date 03/01/15
- Funds must be expended by 06/30/15
- Applications submitted online
- Total funds available for all awards in 02 Year
80,000 - Anticipate up to 4 Awards
- Dependent on quality of applications received
- First offered in the 02 Year
19Mini-Grants
- Two calls for 02 Year first open through
10/06/14 - Preferred uses
- acquisition of pilot data
- analysis of existing data with a specific plan to
publish - development of an intervention
- development of a community-based collaboration
- development of a new research collaboration
between investigators at two or more institutions
within the CTR-IN
20Mini-Grants
- Up to 10,000 direct costs, plus 10 indirect
- Investigator salary NOT allowed
- Earliest start date 12/01/14
- Second call deadline for 02 Year 01/14/15
- Funds must be expended by 06/30/15
- Applications submitted online
- Total funds available for all awards in 02 Year
200,000 - Anticipate up to 20 Awards
- Dependent on quality of applications received
- First offered in the 02 Year
21Round 3 Pilot Grants
- One call for 03 Year RFA end of January 2015
- Earliest start date 07/01/15
- Funds must be expended by 06/30/16
- Applications submitted online
22PEOPLE!
23Your First Call
- Your Local Concierge
- http//ctrin.unlv.edu/?page_id447
24Your First Call Once You Decide to Submit a
Proposal
- Your Local Biostatistician
- http//ctrin.unlv.edu/?page_id186
25Senior Leadership
- Education Mentoring
- Jillian Inouye, UNLV, Director
- Bruce Shiramizu, UH, Mentoring
- Pope Moseley, UNM, Mentoring
- Pat Alpert, UNLV, Assoc Dir, Educ
- Merle Kataoki-Yahiro, UH, Educ
- Craig Molgaard, UMT, Educ
- Design, Epidemiology, Biostat
- Pope Moseley, UNM, Director
- Orrin Myers, UNM, Assoc Dir
- Administrative Core
- Bob Langer, UNLV, PI
- Jim Kenyon, UNR, Proj Coord
- John Foreyt, UNSOM, Eval Dir
- Pilot Grants
- Curtis Noonan, UMT, Director
- Bill Shuttleworth, UNM, Assoc Dir
UNM CTSA Richard Larson
26website
ctrin.unlv.edu
NIGMS Award 1U54GM104944-01A1
27Mountain West CTR-IN Organizational
Structure Governance and Membership
AFFILIATION COLOR CODE UNLV UNR/UNSOM U. New
Mexico U. Montana NIH Other partner
Institutions Outside the 7 state region
Steering Committee Robert Langer, MD, MPH,
Principal Investigator Jim Kenyon, PhD, Project
Coordinator, Partners John Foreyt, PhD, Project
Coordinator, TE Rafael Gorospe, MD, PhD, Project
Officer Maria Canto, DDS, MS, MPH, Project
Scientist
U. of Nevada, Las Vegas - Host U. Alaska
Anchorage Montana State U. U. Alaska
Fairbanks U. of Montana U. of Hawaii
U. of Nevada, Reno Boise
State U. New Mexico State
U. Idaho State U. U. of New
Mexico U. of Idaho U.
of Wyoming
Principal Investigator Robert D. Langer, MD, MPH
Internal Advisory Committee Carolyn Yucha, PhD,
Co-Chair Thomas Schwenk, MD, Co-Chair VPRs of all
13 Partner Universities
External Advisory Committee William T. Cefalu,
MD, Chair Jill G. Joseph, MD, PhD, MPH,
Co-Chair 6 other members from outside the region
Concierge Network
Executive Committee PI 2 Project Coordinators 3
4 with PI KCA Directors CTSC Coordinator
Admin KCA Robert Langer, MD, MPH, KCA
Director Jim Kenyon, PhD, Project Coordinator
CREMCaD KCA Jillian Inouye, PhD, KCA Director
- Mentoring Unit
- Bruce Shiramizu, MD, Associate Director
Education Unit Patricia Alpert, DrPH, Associate
Director
Tracking Evaluation Unit John Foreyt, PhD,
Project Coordinator
UNM CTSC Richard Larson, MD, Coordinator
CTPG KCA Curtis Noonan, PhD, KCA Director William
Shuttleworth, PhD, Associate Director
CRDEB KCA Pope Moseley, MD, KCA Director
Regional Biostatistician Network