Day DateReadingTopic

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Day Date Reading Topic T 10/15 no class
October Vacation Th 10/17 More plant
development T 10/22 Ch. 8 Mechanisms of
morphogenesis Th 10/24 More
morphogenesis T 10/29 Ch. 10 Cell
differentiation Th 10/31 Happy Halloween! Stem
cells T 11/5 quiz on Flowering video
handout Ch. 11 Organogenesis

Th 11/7 More Organogenesis T 11/12
Th 11/14 Ch. 12 Development of the nervous
system T 11/19 EXAM 2 Chapters 2, 7, 8, 10

Drosophila, plants, cell biology,
differentiation Th 11/21 Ch. 9 The saga of
the germ cell T 11/26 More on
reproduction Your term paper is due at the
beginning of class on Tuesday, 11/26 Th 11/28 no
class Thanksgiving Break Also remember there
are two, short writing assignments, each worth 20
points. Pick any topic in developmental
biology (except your term paper topic) and learn
more about it. Then write a two page paper and
include all the sources you used (those can
include any sources including web sites,
newspapers, TV, etc). These are due
anytime.
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In-Class Assignment Draw a human, neural
crest cell with lamellopodia and show the
direction of movement as it crawls over the extra
cellular matrix (ECM).  Include labels or a key
for your drawing.    Show the correct position
of the transmembrane protein integrins (the cell
adhesion molecule for this example) within
membranes throughout your drawing.    Show
three parts of the lamellipodium      1) Actin
microfilaments polymerizing and growing new tips
of the         lamellipodium      2)
microfilaments failing to make contact and
depolymerizing      3) making contact between the
integrins and the ECM and microfilaments       
 contracting as actin and myosin slide past each
other    Show integrins grabbing hold of the
ECM in the front, leading edge of the cell and
letting go at the back of the cell.    Show
the exocytosis and endocystosis pathway moving
integrins from the back of the cell to the
front.    Show microtubules with dynein and
kinesin protein motors attached to them and also
attached to vesicles with integrins.  Include
arrows to show the vesicles are transporting
integrins from the back to front, leading edge of
the cell.
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Ch. 10 Cell Differentiation, Stem Cells
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10.1 differentiation
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10.23 neural crest derivatives
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Fig. 10.19
Fate Specify Determined (committed)
Differentiate the cell becomes the
final cell type differentiation is irreversible
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Fig. 10.19
master regulators like MyoD are transcription
factors that can cause cells to become determined
when the gene is expressed.
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Fig. 10.3 transcription model
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Fig. 10.2
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The story of creating Induced Pluripotent Stem
Cells (IPSC) 2006 present. (2012 Nobel Prize in
Medicine)
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Fig. 10.28
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The story of creating Induced Pluripotent Stem
Cells (IPSC) 2006 present. (2012 Nobel Prize in
Medicine)
Four pivotal genes (each encodes a transcription
factor) Oct3/4 Sox2 Klf4 c-Myc
BOX 10C
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BOX 10C
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