Oxidative phosphorylation - PowerPoint PPT Presentation

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Oxidative phosphorylation

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Oxidative phosphorylation Oxidative Phosphorylation: electron transport chain and chemiosmosis e- trasport chain embedded in INNER mito membrane – PowerPoint PPT presentation

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Title: Oxidative phosphorylation


1
Oxidative phosphorylation
  • Oxidative Phosphorylation electron transport
    chain and chemiosmosis
  • e- trasport chain embedded in INNER mito membrane
  • Composed of 3 transmembrane H pumps
  • Electrons flow through e- chain
  • Loss of energy from e-s powers H pump
  • O2 is final electron acceptor, no O2 no e-
    chain

2
Electron Transport Chain ATP Synthase
3
Electron Transport Chain
  • H ions flow back down gradient through ATP
    synthase
  • ATP synthase harnesses the proton motive force
  • ATP synthase adds a P to ADP to make ATP
  • Do you think the inner mito membrane is permeable
    to H ions?
  • This is the process of chemiosmosis

4
Chemiosmosis
5
Chemiosmosis
  • Chemiosmosis an energy-coupling mechanism that
    uses energy stored in the form of an H gradient
    across a membrane to drive cellular work.
  • The e- chain and chemiosmosis together make up
    the process of oxidative phosphorylation
  • ATP is phosphoralayted
  • Oxygen is necessary
  • ATP/Glucose is 36-38,
  • Oxidative phosphorylation produces 32-34 alone.

6
ATP Yield / Phase of Respiration
7
Remember
  • Aerobic respiration uses oxygn

8
A few alternatives
  • When O2 is not present

9
Fermentation
  • Production of ATP w/o O2
  • This is ANAerboic respiration
  • Glycolysis still in the picture
  • Rember O2 not needed for glycolysis
  • NAD is electron acceptor
  • Two common types
  • Alcohol fermentation
  • Lactic acid fermentation

10
Alcohol Fermentation
  • Pyruvate converted to ethanol, releasing CO2
  • NADH is oxidized to make NAD

11
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12
Lactic Acid Fermentation
  • Pyruvate reduced by NADH
  • So did it gain or loose electrons?
  • Lactate is formed as waste product.

13
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14
Facultative Anerobes
  • Organisms that can do aerobic respiration when
    possible
  • Can switch to fermentation under aerobic
    conditions

15
Glycolysis and Citric Acid Cycle
  • Intermediates of these processes can be diverted
    into a number of other anabolic pathways
  • Biosynthesis is the production of macromolecules
  • Many other compounds can be used to make ATP in
    cellular respiration
  • Other sugars
  • Proteins
  • fats

16
Try these on for size
  • Explain the specific role of glycolysis in
    cellular respiration.
  • Describe the function of water in cellular
    respiration and photosynthesis.
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