HIV and Human Evolution Activity

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HIV and Human Evolution Activity
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• Right now HIV is passed through
• - blood, and sexual fluids
• So only activities like IV drug use or
  unprotected sexual contact will make you
  susceptible
• But what if that changes?
• airborne?

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HIV theories

• We have always known that due to evolution, and
  probability, there had to be people out there
  that were resistant to HIV
• so we found them.
• How could we have found them.
• Nothing is ever 100.... Like paternity

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CCR5 delta 32

• Is a mutation where a section of a gene, is
  deleted
• Chromosome 3- position 21, short arm

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• How did we find people that have a genetic
  mutation that makes them resistant to HIV?

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• HIV- transmitted through bodily fluids (High risk
  behavior)
• Lets say HIV becomes airborne.
• Who lives and whos a goner?
• CCR5- 1 copy (slow progression)
• CCR5/ CCR5- 2 copies resistant

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• Draw 4 punnett squares in your notebook
• Greater than 50 resistant and your descendents
  live.

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• 5-14 of Northern Europeans
• Study done tested 4,166 genotypes
• 0 Amer. Indian, African , East Asian
• Rare in African descended or Asian descended
  populations
• CCR5/ x 2 years before you really get sick
• CCR5/ CCR5 resistant to AIDS

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   Northern Europe as defined by the United
Nations (marked blue)
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• Northern Europe is the northern part or region of
  Europe. The United Nations defines Northern
  Europe as including the following countries and
  dependent regions12
•  Denmark
•  Faroe Islands
•  Estonia
•  Finland
•  Åland Islands
•  Iceland
• Ireland
•  Latvia
•  Lithuania
•  Norway
• Svalbard and Jan Mayen
•  Sweden
•  United Kingdom
•  Isle of Man
• Channel Islands  Guernsey and  Jersey