Immunogenetics - PowerPoint PPT Presentation

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Title:

Immunogenetics

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Title: Author: abc Last modified by: Liiang Created Date: 6/5/2000 6:19:52 AM Document presentation format: – PowerPoint PPT presentation

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Title: Immunogenetics


1
????
  • Immunogenetics

2
  • ????
  • ????????????????????
  • ?????????????????????????????????????????????????

3
?????????
(?)ABO????
  • 1. ABO?????????????

4
(No Transcript)
5
2. ABO?????
6
(No Transcript)
7
(No Transcript)
8
(No Transcript)
9
(No Transcript)
10
  • (?)Rh????????
  • Rh?????

11
  • ???????1???????D?CE???D??????D???CE??????C?c?E?e?
    ?,????????????,????????1-2????????D???????????????
    ??,??Rh(-),???Rh()?

12
(No Transcript)
13
(No Transcript)
14
(?)??????
  • ??????????????,??????????????
  • 1?ABO??????
  • ???O?????A?? B????

15
  • 2?Rh??????
  • ???Rh(-)???Rh()???

16
??????????
17
?????????
  • (?)HLA(Human Leucocyte Antigen)?????
  • ???6p21.3,?????????(polymorphism)???????,?????????
    ?????

18
(No Transcript)
19
  • (?)??????

20
(?)HLA?????
  • ???????,????????????????????????,?????????????????
    ??????????????????????????????????????????????????
    ????

21
1?????
  • ???????????????ABO?????HLA????,?????????????,?????
    ?????????????,???????(histocompatibility),??????
    ???

22
  • 1)????

a)ABO????
b)Rh???? Rh()???????Rh(-)???
23
  • 2)??????
  • ????(autograft)

  • ????
  • ????(isograft)(??????)
  • ??????(allograft,homograft)

  • ?????
  • ????(xenograft)

24
  • ???(???????)
  • (a)ABO?????,???????
  • (b)HLA????????????????????HLA?????HLA???(HLA
    haplotype)?????????HLA??????HLA????

25
(No Transcript)
26
  • ?????
  • ????
  • ?????????
  • ??HLA??????
  • ??HLA?????????
  • HLA??????????
  • ????HLA????????
  • ?A?B?DR???6?????,??????HLA???????

27
  • (c)????????
  • ??????(T?B) ???? ??
  • T() B()?????????HLA??I??????-----????
  • T(-) B()?????????HLA??II??????------?????

28
  • ????(??????)
  • ???????????
  • ?????????(??),???????????(??),????????(graft-versu
    s-host disease, GVHdisease)??,??????????????
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