Results

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Results

• Animals with recognition displayed increased BDNF
  in the iTC, CA1 of the hippocampus, the diagonal
  band, basolateral amygdala and the anterior
  cingulate, medial frontal, entorhinal and
  pyriform cortices.
• Activity in Visual AND Olfactory areas of cortex
• Suggests that reorganization of neural circuits
  underlying the visual recognition of lambs or the
  integration of olfactory/visual information is
  occurring even at this time (though accurate
  behavioral recognition at this stage can only be
  olfactory).

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Solid Data?

• Experimental group engaged in 4.5 hours of
  maternal behavior not present in the control.
• Stress in the control group?

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Mapping of Olfactory Memory Circuits
Region-Specific c-fos Activation After
Odor-Reward Associative Learning of After its
RetrievalSophie Tronel and Susan J. Sara
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The Basics

• Looking for post-training activation of a network
  of closely related brain regions, particularly in
  the frontal cortex and the basolateral amygdala
  (BLA), that is specific to the learning of an
  odor reward sensation via immunoreaction to c-fos
• Retrieval does not differentially activate the
  same regions (amygdala is not active after
  retrieval whereas the lateral habenula shows
  activity).

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Co-activation of the amygdala, hippocampus and
inferior frontal gyrus during autobiographical
memory retrieval.

• Greenberg et al.

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The Basics

• Functional MRI utilized to investigate the role
  of the medial temporal lobe and inferior frontal
  lobe regions in autobiographical recall.
• Autobiographical Memory constructed of memories
  for personal life events.
• Tulvings autonoetic conciousness
• Dependent upon medial temporal and pre-frontal
  regions
• The three predictions...

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fMRI Results

• Amygdala Significant 3 way interaction of
  retrieval condition, hemisphere, and slice.
• Hippocampus Greater activation during
  autobiographical retrieval and left hemisphere
  bias
• IFG same as amygdala plus a posterior gradient
  of activation in the right hemisphere during
  autobiograhical retrieval

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Group averaged hemodynamic responses
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Schematic illustration of results from the
correlational analysis for each retrieval
condition.
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Discussion

• Greater activity in left amygdala, hippocampus,
  and right IFG relative to semantic.
• Tighter coupling of activity across these three
  regions relative to semantic memory
• Cohesion between medial temporal and ventral
  frontal lobes.
• IFG contributes to both types of memory but
  activation prolonged in semantic

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The neural origins of specific and general
memory the role of the fusiform cortex

• Rachel J. Garoff, Scott D. Slotnick, Daniel L.
  Schacter

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The Basics

• Conducted an event related fMRI study to observe
  fusiform cortex activity
• Memory expression specific/verbatim vs.
  non-specific recognition of the general sense
• Neural basis for non-specific recognition?
• The Fusiform Cortex significance of activity.

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Behavioral responses associated with same similar
and new items at recognition.
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Results

• Activity in the right fusiform gyrus, extending
  into the parahippocampal gyrus, during encoding
  was preferentially associated with specific
  recognition.
• Significant difference between encoding related
  activity associated with non-specific recognition
  and baseline in left inferior frontal gyrus.