Centrifugal Separator for Pharmaceutical and Biotechnology Applications

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Centrifugal Separator for Pharmaceutical and
Biotechnology Applications

• Tomoe Engineering Co., Ltd.

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Outline

• Tomoe Engineering Co., Ltd. Concluded a technical
  assistance agreement with Sharples Corp., U.S.,
  and initiated the manufacture and sale of
  centrifuge in 1950.
• Alfa Laval purchased Sharples Corp. in 1990 and
  then Tomoe and Alfa Laval kept cooperated
  relationship.

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Characteristics of Tomo-e Tubular Centrifuge

• High G-Force 20000G
• GMP Apply U.S.FDA European Spec.
• SIP Apply 121? Spec.
• Many Machine Line-up Several Capacity

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Performance, ASM260

• Typical performance of ASM260
• Colitis germs 100L/Hr
• Colitis germs (mash) 50L/Hr
• Lactic acid bacilli 70L/Hr
• Vaccine 50L/Hr
• Cryo 200L/Hr
• Yeast Cell 500L/Hr

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Laboratory Use, T-1

• Bowl Capacity 0.27L
• Max. G-Force 62000G
• Elec. Power 0.1Kw
• Dimension 430250800

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Pilot Plant Use, ASM100

• Bowl Capacity 2.5L
• Max. G-Force 20000G
• Elec. Power 1.5Kw
• Dimension 7604001150

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Middle Size, ASM160

• Bowl Capacity 5.5L
• Max. G-Force 17000G
• Elec. Power 2.2Kw
• Dimension 7808701500

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Structure of ASM160
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ASM160 PL VBNF
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Large Centrifuge, ASM260

• Bowl Capacity 7.8L
• Max. G-Force 20000G
• Elec. Power 7.5Kw
• Dimension 10108701630

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ASM260VBNF
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Another Type and Specifications

• Tomo-e Tubular Centrifuge
• Type Unit T-1 ASM100 ASM160 ASM260 ASM460 ASM660
  
• RPM rpm 50,000 19,000 17,000 17,000 15,000 12,
  200
• G-Force G 62,000 20,000 17,000 20,000 20,000
  15,000
• Bowl Dimension mm 44f201 95f457 105f720 124f7
  20 160f720 190f1328
• Bowl Capacity L 0.27 2.5 5.47 7.8 13.2 33.7
• Elec. Power Kw 0.1 1.5 3.7 7.5 18.5 37
• Typical Capacity L/Hr 5 30 60 100 150 300

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Instruction for Drag Bushing
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Installation for Spindle/Bowl
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Installation for Bowl Assy
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Installation for Idlar Assy Bearing Assy
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Installation for Bearing Assy No.1
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Installation for Bearing Assy No.2