MCP??????????????????????? - PowerPoint PPT Presentation

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MCP???????????????????????

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galectin-3 MCP Modified citrus pectin one bullet, ... – PowerPoint PPT presentation

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Title: MCP???????????????????????


1
MCP???????????????????????
  • ??? ???
  • ?????????????????

2
?????????????
  • ???????????????????????
  • ??????????????????????9????,??????????????1218???
  • ??1940?Cartells???????????????????,??????????????
    ??????????????
  • ???????????????????????????????????????.
  • ????????????5??10??20???????37?28?24,?????????1
    6,???????1.3?

3
MCP(??????, Modified citrus pectin)
  • MCP??b-????????????gal-3?????,?????????galectin
    -3????????????galectin-3??????????????????????

4
MCP(??????, Modified citrus pectin)
  • one bullet, multiple targets !

5
  • ??
  • ????????,??Galectin-3???????????????????(MCP)???
    ?????Endostatin(ES)???????????????????????????????
    ??

6
  • ??
  • ??160?Balb/c??????????????MCP?????ES?????MCPES??
    ????MCP????????0.05mg/ml,ES???????2
    mg/kg,????,?????????????????????????7?14?21?28????
    ??????10???,
  • ??????????????????,?????????????????????(ELISA)??
    ????????????-3(galectin?3)?????????C(VEGF-C)???

7
  • ??
  • 1 ??????
  • ?????????????????,?7??????????????????????,?14????
    ?????????????????21?????????????????????????8?????
    ?????(??1)???????????????????HE??????????????

8
  • 2 ??????
  • ??1?2?,???????????????????(Pgt0.05)???3?4?,????????
    ,MCP???????????????????????,??????????(Plt0.05)?

9
  • 3 ???????
  • ??1?2?,??????????????????(Pgt0.05)???3?4?,????????,
    MCP?????????????????????,??????????(Plt0.05)???????
    ??????2-4 ?

10
  • 4 ??galectin?3????(?5)
  • ?????????????????galectin?3??????,?????,??????Ga
    lectin-3?????????????????????????(Pgt0.05)??5?

11
  • 5??VEGF-C??????(?6)
  • ?????????????????VEGF-C??????,?????,??????VEGF-C??
    ???????????????????????(Pgt0.05)?

12
??
  • 1??????????,Galectin-3???????????????????????????(
    ??????)
  • 2?MCP???????????????????,ES??????????????,????????
    ???????
  • 3?MCP????????????????,?MCP??ES???????????????????
  • 4?MCP?ES???????????????????Galectin-3?VEGF????

13
??
  • 1.?????????????
  • 2.??????????,????
  • GAL-3 3.???????????????????
  • ??????????
  • 4.??????????
  • 5.???????????????????
  • ??????????
  • .MCP????gal-3??????????
  • ?,????????????
  • ?MCP??????????????gal-3
  • ???????????????????
  • ?????????????
  • MCP
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