(Liver Flukes)

1
????????????? (Liver Flukes)
2
????????????? (Liver Flukes) - ?????????????
??????????????????????????????? ???
??????????????????????? Family Opisthorchiidae C
lonorchis sinensis Opisthorchis
viverrini Opisthorchis felineus
3
Family Fasciolidae Fasciola hepatica Fasciola
gigantica Family Dicrocoelidae Dicrocoelium
dendriticum Eurytrema pancreaticum
4
Family Opisthorchiidae Clonorchis
sinensis Opisthorchis viverrini Opisthorchis
felineus - ??????? ??????????? ????????????
Lancet shape - ???? ??? Clonorchis sinensis
??????????
5

• ????????? Reproductive organ
• 1. Oval Ovary
• 2. Testes
• Clonorchis sinensis ???? branch
• Opisthorchis viverrini ???? lobe
• Opisthorchis felineus ???? lobe

6
3. Vitelline gland Clonorchis sinensis
???? cluster Opisthorchis viverrini ????
transverse Opisthorchis felineus ????
branch

• ????????????
  ????????????????????????????

7
(No Transcript)
8
Opisthorchis viverrini
Clonorchis sinensis
9
- ?????????????
Clonorchis sinensis ?????????? ???
??????? ???????
?????? Opisthorchis viverrini ????
??? ??? ???
??????????????????????
Opisthorchis felineus ????????????
10
Opisthorchis viverrini
????????????? (Distribution) -
?????????????? ????????????????
????????????????? ????????????????
???????? - ?????????? ???
??????????????
????????????????
11
??????? (Morphology) - ??????? ??? Lancet-shape
(Posterior ???????? Anterior) - ?????????????
???????? ????? uterus ?????????? - ???? ???
5.5-9.6 mm , ????? 0.8-1.7 mm - sucker 2 ???
?????????? - Excretory bladder ???? sac-like
tube ???? - Testes 2 ??? ???? lobe -
??????????????? ??Operculum , Shoulder , Knob
(????19-29 X 12-17 um) - ????? 1 ??? ??????
2000-4000 ??/???
12
(No Transcript)
13
(No Transcript)
14
(No Transcript)
15
??????? (Life cycle) - Adult ????????????????????
???? ??? Definitive host (???? ??,?????
??????) - ?????? ??? (1st I.H. Bithynia
spp.) ??? - ?????????????????????????????????
????????????????? cercaria
16
- cercaria ??????????? 2nd I.H. ??????????
????????? ??? ???????????? (Cyclochellicthys
siaja) ?????????????? (Hampala dispar)
??????? (Puntius orphoides) - ????? ?????
??????????????????? metacercaria
??????????????????????? ??????????????????????
???????
17
(No Transcript)
18
(No Transcript)
19
Miracidium ?????? ???
20
??? Bithynia sp.
21
Cercaria ????????????????
22
(No Transcript)
23
?????????? (Epidemiology) - ?????????? ??????
????????? (??????? ?????????) ???????
(?????????? ??????) - ???????????????
??????????????? 5 ??? ?????? 35 ????
10 ?? - ??????? ?????? 80 90
24
?????????? (Pathology) - ???????????????????????
??????????????? ????????????????
?????????????????????? - ??????????????????????
?????????????
25
- ???????????????????????????????????
?????? 1. ???????????? 2. ??????????????? 3.
????????? (?????) 4. ????????????? ??????????????
???????????????????? ????????? ????????
26
(No Transcript)
27
????? (Sign and Symtom) - ???????????????????????
?????? ????????????? ????????
??????????????? ????????????????????? 1.
????????????????? ??????? ??????
100-200 ??? ???????????? 2.
?????????????? ?????????????
????????????????????? ??????????
????????????????????? ????? 1000 ?? ?????????
1 ????
28
3. ???????????? ??????????????????????
???????? ????????????????????? ????????????????
??????????????????????? ?????????????? ??????
??????????? ????????????????? ???????????????????
?????????????????? ????? 3000 ?? ????????? 1 ????
29
4. ??????????????? ?????????????????????
????????????????????????? ?????????????
??????????????? ???????? ?????????? ?????
?????????????????????????? ?????????
??????????????????????
30
??????????????? (Diagnosis) 1. ???????????????????
???? 2. ???????????????????? ????????????
???????? ????????? ???????????????? ????????
(Treatment) ????????????? Praziquantel
31
??????????????????? (Control and Prevention) 1.
???????????????????????????? ?????? ????????
???? 2. ???????????????????? 3.
????????????????????????? 4. ?????????????????? 5.
??????????
32

• Family Fasciolidae
• Fasciola hepatica
• Fasciola gigantica
• ??????????????????? ??? ??? ????
• ????????????? Ectopic foci ???????????????
• ??????? ??????????? ??? ?????????? ????

33

• ??????????????????? 2 ?????????????????
• Fasciola hepatica ???????????????
• Fasciola gigantica ??? ??????????
• (Bamboo
  leaf)
• ???????????? Fascioliasis ???? Fasciolosis
• ????? ???? The sheep liver fluke

34
(No Transcript)
35
Fasciola hepatica
36
Fasciola gigantica
37
????????????? (Distribution) - Fasciola
hepatica ????????????????? ??????? ??????
?????????? ????? - Fasciola gigantica
??????????? ??? ???????????????????
38
??????? (Morphology) - ?????????? 20-30 mm
????? 13 mm - ???????????? (spiny tegument) -
????????????????????????????? Cephalic cone -
Oral sucker ?????? 1 mm Ventral sucker ????
1.6 mm ??????????
39

• Pharynx ??????? ?????????????
• Testes ?? 2 ??? ????????
• - Ovary ???????????????????????
• Anterior testes
• - ????????? ??? ovoidal ?? operculum
• ????? ????????????????
• ???? 130 150 X 60 80 um

40
??????? (Life cycle) - 1st I.H. ?????? ???
Lymnaea sp. (Radix sp.) - 2nd
I.H. ?????? ??????
41
Family Dicrocoelidae Dicrocoelium dendriticum -
????? ????? ??????? ??????? ???????
1st I.H. ??? Land snail 2nd I.H.
??? Ant - D.H. ?????? ???, ???
42

• Eurytrema pancreaticum
• ????? ??? ??? ???????? ???????
• 1st I.H. ??? Land snail
• 2nd I.H. ??? Grasshopper , ant
• D.H. ?????? ??, ??????

43
(No Transcript)
44
Dicrocoelium dendriticum
45
Eurytrema pancreaticum