Occupational Lung Diseases Hypersensitivity Pneumonitis, Asbestosis, Silicosis - PowerPoint PPT Presentation

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Occupational Lung Diseases Hypersensitivity Pneumonitis, Asbestosis, Silicosis

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Mineral Dust Pneumoconiosis Fibrogenic Asbestosis Silicosis Berylliosis Coal worker s pneumoconiosis * * * * Title: Slide 1 Author: user Last modified by: – PowerPoint PPT presentation

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Title: Occupational Lung Diseases Hypersensitivity Pneumonitis, Asbestosis, Silicosis


1
  • Occupational Lung Diseases Hypersensitivity
    Pneumonitis, Asbestosis, Silicosis

2
Occupational Lung Diseases Hypersensitivity
Pneumonitis, Asbestosis, Silicosis
  • Penyaji Materi
  • dr.Sinatra Gunawan,MK3,SpOk
  • Referensi
  • Amer Rassam MD1, Gerry San Pedro MD2, Daniel
    Banks MD1.
  • Department of Internal Medicine
  • LSUHSC-Shreveport

3
Occupational Lung Disease
  • OLDs have been recognized for centuries.
  • Lung illness was realized to be part of miners
    life even in the 16th century.
  • Governments of many countries have implemented
    formal policies of workers compensation.
  • The relationship between exposure at work and
    disease is underestimated.

4
Occupational Lung Disease
  • Although OLDs are thought to be preventable, they
    continue to occur.
  • The magnitude of the problem is underestimated
    due to long latency.
  • Wearing protective respiratory devices is an
    unrealistic expectation.
  • The most notorious failures of OLD have occurred
    in reported epidemics of silicosis in the
    American workplace.

5
Occupational Lung Disease Inhaled Dusts
6
Occupational Lung Diseases
  • Hypersensitivity pneumonitis
  • Organic dusts (Byssinosis)
  • Inorganic dusts (Asbestosis,
  • Silicosis, Berylliosis, and
  • Coal workers pneumoconiosis)

7
Hypersensitivity pneumonitis
General
  • Immune mediated granulomatous reaction
  • Reaction to organic antigen
  • Not many people get it
  • Poorly-formed granulomas are typical
  • It has a wide range of causes

8
Hypersensitivity pneumonitis
Causes
  • Moldy hay (thermophilic actinomycetes)
    farmers lung
  • Pet birds bird fanciers lung
  • Grain dusts
  • Isocyanates
  • Air conditioning system

9
Hypersensitivity pneumonitis
Clinical
  • Acute, subacute, and chronic forms
  • Recurrent chest infiltrates with fever WBC
  • Slowly progressive pulmonary fibrosis
  • Diagnosis by history
  • Serum precipitins are non-specific
  • CXR Recurrent infiltrates fleeting
  • Treatment - remove pt from offending antigen

10
Byssinosis
  • Inhalation of cotton, flax, or hemp dust
  • Not immune related
  • Early stage - Occasional chest tightness
  • Late stage Regular chest tightness towards
    the end of the 1st day of the workweek Monday
    chest tightness
  • Frequency of symptoms slowly increases

11
Mineral Dust Pneumoconiosis
Nonfibrogenic
  • Iron, Zirconium, Tin, Barium, and Aluminum
  • Striking CXR Dense nodular opacities
  • No symptoms, physical findings, or impairment.

12
Mineral Dust Pneumoconiosis
Fibrogenic
  1. Asbestosis
  2. Silicosis
  3. Berylliosis
  4. Coal workers pneumoconiosis
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