Impact of Attenuation Correction by Simultaneous Emission/Transmission Tomography on Visual Assessment of 201Tl Myocardial Perfusion Images

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Impact of Attenuation Correction by Simultaneous
Emission/Transmission Tomography on Visual
Assessment of 201Tl Myocardial Perfusion Images

• Journal of Nuclear Medicine 1999
• 401301-1309
• Reporter Hung-Jen Hsieh

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Introduction

• It has been shown that for subjects with a low
  likelihood of CAD, attenuation correction(AC)
  improves the specificity of defect detection in
  the inferior wall.
• The aim of this study was to investigate the
  effect of AC on the visual interpretation of the
  RCA and LAD regions in CAD patients.

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Material And Methods

• Patients Selection
• Cardiological Evaluation
• Significant stenosis was defined asgt70
• luminal diameter reduction, with normal wall
  
• motion on ventricular angiography.
• ECG Q-wave and elevation of CPK enzymes,
• together with evidence of an akinetic
  segment
• supplied by a major epicardial vessel with
• thrombosis, was necessary to diagnose MI.

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• Stress/Reinjection Perfusion Imaging
• Acqusition Protocol
• Visual Analysis Five point rating scale
• Statistical Analysis The significance of the
  differences between ROC curves was tested by
  comparing the areas under the ROC curves(AUCs).

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Results And Discussion

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Conclusion

• AC significantly affects the visual
  interpretation of 201Tl stress/4 h-delayed SPECT
  images.
• This study confirmed the increase in
  specificity obtained with AC in the RCA
  territory. However, in the population considered,
  the studied AC was deleterious for the LAD
  territory assessment.

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• Thanks for your attention!