Cigarette Smoking Increases the Risk Of Formation and Rupture of Intracranial Aneurysms

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Cigarette Smoking Increases the Risk Of Formation
and Rupture of Intracranial Aneurysms

• Shelebra Bartley
• Masters Project
• Dr. Grimes

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If you are a woman with a brain and you smoke
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Your brain will EXPLODE
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Quick Review

• An aneurysm is a weakened spot on a blood vessel
  that balloons out and fills with blood
• The aneurysm can put pressure on surrounding
  nerves or it can rupture causing blood to spill
  into the surrounding tissue

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3 Types of Aneurysms

• Fusiform
• Berry
• Lateral

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Berry Aneurysm

• Aka saccular aneurysm
• Attached by a neck or a stem to an artery
• Accounts for 90 of all aneursyms

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Berry Aneurysm
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How to diagnose an Aneursym?

• CT angiography
• Magnetic Resonance Angiography (MRA)
• THE GOLD STANDARD
• INTRA-ARTERIAL CATHETER ANGIOGRAPHY

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Arteriogram
CT Scan
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Treatment Options

• REFER
• REFER
• REFER

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Education

• Stop smoking
• Stop drinking
• Control blood pressure

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Helsinki Research Results

• Studied 278 subjects
• Age 15-60 with subarachnoid hemorrhage
• 314 patients in control group
• Research team studied the effects of cigarette
  smoking, alcohol intake and HTN on the rupture of
  intracranial aneurysms

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What they found

• Current cigarette smoking especially in women is
  an independent risk factor for formation and
  rupture of intracranial aneurysms
• Current smokers and previous smokers had more
  aneurysms than did those who had never smoked
  regularly

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Johns Hopkins Research

• Angiography confirmed intracranial aneurysms
• 419 patients dx with intracranial aneurysm
• 127 had multiple aneurysms
• Women and hx of smoking

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Anybody need a smoke break?
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University of Colorado

• 92 of patients with aneurysms larger than 24mm
• 78 of patients with aneurysms ranging in size
  from 13.3mm to 24mm
• 66 of patients with aneurysms smaller than 13mm

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WERE

• SMOKERS

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IN CONCLUSION

• Evidence has shown that cigarette smoking
  increases the rate of formation and rupture of
  intracranial aneurysms
• Cigarette smoking and female gender can be
  identified as an independent risk factor

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If you are a woman with a brain and you
smokeyour brain will explode