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HSS4331

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Gamete Donation. Sperm donation. Relatively simple. Donors are usually friends or family ... Transplanting non-human gametes or embryos into a human is prohibited ... – PowerPoint PPT presentation

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Title: HSS4331


1
HSS4331 Introduction to International Health
Theory
  • Nov 24, 2008 Medical (Reproductive) Tourism

2
Upcoming Events
  • Wednesday Nov 26, 630pm, UC Terminus Hunger
    Banquet featuring Prof Paul Haslem. 5 in
    advance (from International House) or 6 at the
    door
  • Thursday Nov 27, 6pm, UC Terminus - Student
    Refugee Program Awareness Night free of charge
    and there will be pizza.
  • Monday Nov 24, 5-7pm, RGN Amph A, Dr Jane
    Philpott on Canadians engaging in global health

All are eligible for your summaries
3
Today.
  • Were going to talk a little bit about some of
    the work I currently do
  • Some of it is coordination with Assisted Human
    Reproduction Canada (AHRC)
  • But nothing I say or present today should
    necessarily be considered the position of AHRC

4
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5
In General.
  • What is medical tourism?

1. The act of (typically Western) medical
professionals doing abroad to do good work, but
in reality functioning as gawking tourists 2.
The act of (typically Westerners) going abroad
(to typically developing countries) to seek
medical care.
6
The First Type
  • The act of (typically Western) medical
    professionals doing abroad to do good work, but
    in reality functioning as gawking tourists
  • The danger of every international health project
  • Whom does it really benefit?
  • cowboy global medicine
  • Sustainable?

7
The Second Type
  • The act of (typically Westerners) going abroad
    (to typically developing countries) to seek
    medical care.
  • Growing in popularity
  • Often tied to other tourist activities
  • Negative downstream consequences may not be
    immediately obvious

EXAMPPLE Reproductive medical tourism
8
Terminology
  • Infertility
  • One year of unprotected sex without conceiving a
    child
  • Includes both sterile and subfertile people
  • Sterile
  • Will never conceive without medical assistance
  • Subfertile
  • May still conceive without medical assistance

9
Infertility
  • About 15 of couples will be defined as
    infertile
  • But this only accounts for those who actually
    seek services likely an underestimate
  • -1990 estimate gt1 billion women worldwide are
    affected by infertility
  • -only covers those of reproductive age who have
    been diagnoses
  • On the increase in Western nations

10
Why Is Infertility On The Rise?
  • People waiting till later in life to have kids
  • Obesity and diabetes are on the rise
  • Environmental contaminants may be affecting
    hormone levels

11
Terminology
  • Assisted Human Reproduction (AHR)
  • Anything involving helping infertile people
    become fertile
  • Assisted Reproductive Technologies (ART)
  • Technologies related to AHR
  • Some define it only as technologies involving
    embryo formation outside the body

12
IUI
  • Intra-uterine insemination
  • Artificial presentation of sperm into the vaginal
    canal
  • turkey baster method

13
IVF
  • In Vitro Fertilization
  • Creation of embryo in a dish, and returning it to
    the womb
  • test tube babies
  • Considered the vanguard ART technology

14
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15
ICSI
  • Intra cytoplasmic sperm injection
  • Done in conjunction with IVF
  • Grab a sperm and force it into an egg
  • Used when sperm just cant get the job done by
    themselves

16
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18
Gamete Donation
  • Sperm donation
  • Relatively simple
  • Donors are usually friends or family
  • Anonymous donors are rare and in demand
  • Egg donation
  • Very invasive
  • Expensive procedure
  • Hard to find donors

19
Surrogacy
  • A surrogate mother is a woman who agrees to
    gestate and give birth to a baby for someone else
  • Scenarios
  • Surrogate receives sperm via IUI and uses her own
    egg
  • Surrogate donates egg, embryo created via IVF
    (with or without ICSI)
  • Another egg is used, embryo created via IVF (with
    or without ICSI)

20
Statistics
  • Canada
  • about 6500 IVF embryo transfers per year
  • USA
  • About 120,000 IVF procedures per year
  • UK
  • About 35,000 IVF procedures per year
  • Europe
  • About 300,000 IVF procedures per year

21
Costs
  • One attempt at IVF costs 8000-16000
  • ICSI costs extra
  • Donated sperm costs 200-600 (from US centre)
  • Donated egg costs 500-20000 (from US source)
  • Surrogate services cost 50,000 or more

22
The Law
  • 1993 Royal Commission on New Reproductive
    Technologies
  • 2004 Assisted Human Reproduction Act
  • 2006 Assisted Human Reproduction Canada
  • 2009 rules spelled out in the Act begin to be
    enforced

23
Canadas Act
  • Human cloning prohibited
  • Sex selection prohibited
  • In vitro gene alteration prohibited
  • Transplanting non-human gametes or embryos into a
    human is prohibited
  • Transplanting human gametes/embryos into a
    non-human for the purposes of creating a human
  • Create chimeras/hybrids

24
Canadas Act
  • No payment for surrogacy
  • No paid brokerage for surrogacy
  • No payment for gametes
  • No paid brokerage for gametes
  • etc

25
The Law
  • Laws in different countries vary dramatically
  • In the US, it varies from state to state
  • In Australia, only one state has clear
    regulations
  • In UK, rules are well defined and monitored
  • In Israel, its the wild wild west
  • Etc.

26
So.
  • Lets say youre an infertile couple in Canada
    who wish to
  • Select sex of your baby
  • Pay for a surrogate mother
  • Pay for a sperm or egg donor
  • Pay less for a baby

What do you do?
27
You Go Abroad
  • Example
  • In Virginia Mason medical centre in Seattle, 33
    of patients are Canadian, most seeking to buy
    donor eggs
  • In India, reproductive tourism is a 450
    million industry

-gt Reproductive Tourism
28
South Asia
  • Currently, parts of the USA are the most popular
    destinations for reproductive tourists
  • But India is fast becoming an important
    destination

29
India
  • Surrogate mother in India costs lt5000
  • Plethora of doctors, all English-speaking
  • Case study
  • A British couple in 2006 spent 60,000 pounds on
    IVF in the UK without success, so they went to
    India and paid 3,300 for a surrogate mother

30
So, Whats The Problem?
  • From an international health/development point of
    view, what are the issues?

31
The Issues
  1. Protection for couples travelling abroad
  2. Protection for women selling services in poor
    countries

32
The Issues
  • Couples are bypassing the laws of their own
    countries should they be prosecuted?
  • Informed consent how informed are these women?
  • Choice. In many places, how can we guarantee
    that women are not being forced to participate?

33
More Issues
  • India is popular also because of its familial
    laws
  • In UK, a surrogate mother can change her mind and
    claim the baby as her own any time within the
    first 2 years of life
  • In India, the surrogate loses all rights to the
    baby at the point of delivery

34
More Issues
  • Is remuneration fair? Should surrogates be paid
    global market rates?
  • Social stigma of carrying the child of a man who
    is not your husband
  • Loss of control of ones body, as client and
    doctor have a vested interest in the surrogates
    nutrition and activities

35
Even More Issues
  • Must protect vulnerable infertile Westerners from
    being fleeced by dishonest doctors and surrogates
  • In instances of extreme poverty, is there really
    such a thing as choice for a surrogate?
  • Compare to instances of choice for an
    impoverished woman who chooses prostitution

36
Even More Issues!
  • What kind of health follow-up are surrogates
    given?
  • Are they given post natal care, especially after
    the baby has been given up?
  • What reproductive effects do surrogates suffer
    from?
  • Giving birth is dangerous
  • Potential for surrogate to become infertile

37
Legal Issues
  • A child born to a surrogate mother in India what
    are the legal steps to get it into the country of
    the client?
  • Formal adoption procedures?
  • Can a surrogate mother in India benefit from
    parental laws of the clients country?
  • Does she have the 2 year leeway in the UK?

38
Cross Border Reproductive Care
  • Why is this the preferred terminology?

39
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40
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41
What Needs to Be Done?
  • What do you think?

42
Summary of the Ethical Issues
  • Misdirection of financial resources those who
    seek services abroad deny their resources (i.e.,
    outgoing funds) to their home community
  • Misdirection of medical resources those who
    provide services to tourists are denying their
    services to their home community
  • Implications of insufficiency the act of
    seeking services abroad implies that services are
    insufficient, in quantity, type, timing or
    affordability, in the home community
  • Criminality if service seeking abroad is done
    to avoid laws at home, should the international
    community consider this criminal behavior? Is the
    provision of services therefore the abetting of
    such criminal behavior?
  • Quality control if the health and welfare of
    tourists is a concern, how do we control for
    the quality and validity of medical services
    provided outside of ones administrative
    jurisdiction?
  • Robustness of informed consent are tourists
    provided with adequate and accurate
    representation of actual risks and probable
    success rates? Brokers may misrepresent facts.

The above may apply to all types of medical
tourism
43
  • The following issues are particularly relevant to
    the seeking of surrogate services in the
    developing world
  • Robustness of informed consent this issue, as
    it pertains to the surrogate, is quite separate
    from that pertaining to the tourist. Social
    downstream impacts must also be communicated (eg,
    is a conservative society ready for a woman to
    carry baby for two gay men will husband respond
    well to wife carrying the baby of another man
    specific religions eg, Muslim- concerns)
  • Custody rights rights vary from country to
    country. To what extent is the industry
    affecting the drafting of custody rights
    legislation?
  • Cultural appropriateness see (a) economic
    attraction of the industry may bring it to
    societies presently unprepared for some of the
    implications, eg gay parents, single mothers,
    carrying a child that is not your husbands
  • Quality of care surrogates physical health is
    maintained, but only to the extent that it
    benefits her pregnancy. What of social and
    mental health? What of her removal from
    care-giving milieu of her own community? If
    clinic provides her diet, does she still cook for
    her family?

44
  • Limits of care While the surrogates medical
    health is of prime importance during pregnancy,
    does this care end upon birth of the child? Is
    there an investment in post-partum care? To what
    extent does economics affect this trend? (Eg, a
    regular surrogate should be maintained in good
    health due to her ability to perform again.)
  • Remuneration one reason tourists seek service
    is reduced cost abroad. But while remuneration
    for the surrogate is likely above what she would
    otherwise earn, it is likely below global market
    rates.
  • Abortion selective reduction is a common
    occurrence in ART. Is surrogate aware and
    culturally responsive to this likelihood?
  • Medical advocacy clinician responds to needs of
    the tourist. Is it a conflict of interest to
    also be care-giver to the surrogate?

45
What We Are Doing
  • Step 1 bring together ART regulatory bodies
    from key nations
  • Step 2 agree that these are issues worth
    considering
  • Step 3 Collect data!
  • Step 4 to be determined

46
Achievable Goal
  • Establishment of international body to
  • Monitor extent of reproductive tourism
  • Set forth international guidelines for
    appropriate ART/AHR care
  • Monitor quality control for doctors offering
    services to international clients
  • Monitor rights abuses of local women offering
    their reproductive tissue and services
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