Polio Eradication Initiative New Solutions to Longstanding Challenges

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Global Polio Eradication InitiativeRecommendatio
ns of the Advisory Committee on Polio
Eradication (ACPE)
12 October 2005
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Polio eradication 3 challenges

• Nigeria
• Suspension of immunizations leads to outbreaks in
  surrounding countries highest burden of disease
  of any country
• India / Egypt
• Highly efficient virus transmission due to high
  and dense populations
• Distant importations
• Indonesia, Yemen, Angola

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1. Impact of synchronized immunization campaigns
in west central Africa
2004
Jan May 2005
Since June 2005
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2. India / Egypt impact of mOPV
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3. Impact of outbreak responses
Polio in 2005
-More cases due to importations than endemic cases
Yemen
-Outbreak curbed
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Recommendation 1 Expanded use of monovalent OPV
Monovalent OPV use by end-2005/early 2006
Monovalent OPV use under consideration
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Recommendation 2 Enhanced outbreak response

• VERY RAPID plan within 72 hours respond
  within 4 weeks.
• LARGE minimum 2-5 million children.
• HIGH QUALITY house-to-house
• DURATION at least 3 rounds.
• VACCINE monovalent OPV

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Recommendation 3 Nigeria

• Increase quality of immunization activities to
  reach every child
• Increase number of supplementary immunization
  campaigns
• Use monovalent OPV, to maximise impact of each
  contact
• ACPE will continue to monitor progress in Nigeria