Enhanced Diabetic Manager

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Enhanced Diabetic Manager

• SBIR Presentation
• ODU Green Team 2008
• May 2008

2
Outline

• The Problem
• Daily Routine
• Complications
• The Diabetic Calculation
• Market
• Risks
• Plans

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The Problem

• 1,500,000 new cases discovered each year
• 8 (roughly about 21,000,000) of Americans have
  some form of diabetes
• 4 of Americans are undiagnosed
• Diabetes cost the U.S. an estimated
  174,000,000,000 last year alone

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Diabetics in U.S. Population
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Diabetic Market Analysis
6
Diagnosed Diabetic Market Analysis
7
Problem Statement

• Diabetics encounter lifelong challenges managing
  their disease.

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Morning Routine
9
Daytime Manual Injection Routine
Estimate Carbs
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Daytime Insulin Pump Routine
Estimate Carbs
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Daily Complications

• Hypoglycemia (Low Blood Sugar)
• Irreversible brain death
• Coma
• Seizure

• Hyperglycemia (High Blood Sugar)
• Death
• Hyperosmolar coma
• Shock

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Long Term Complications

• Diabetic Neuropathy Nerves
• Amputation
• Heart Disease Stroke
• Diabetic Nephropathy Kidneys
• Diabetic Retinopathy Eyes
• Blindness

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Improper Management of Glucose
PERCENT
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Benefits of Stabilized Glucose Levels

• 54 decrease in kidney disease
• 60 decrease in nerve disease
• 76 decrease in eye disease
• Overall well-being

Diabetes Care, volume 31, number 3
http//care.diabetesjournals.org/misc/econcosts.pd
f
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Glucose Management Statistics
MILLIONS
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The Diabetic Function
D(g)

D(i)
D(c)
D(t)
D(e)
Exercise burns carbohydrates
Exercise lowers glucose levels when burning carbs
Carbs contain glucose
Different insulin at different times
Exercise affects blood glucose
Insulin injection stabilizes glucose levels after
carb intake
Basal dose taken in morning
Carbohydrate intake requires bolus insulin dose
Insulin breaks down glucose
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Major Functional Components
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What eDM will do
D(g) eDM
eDM
eDM
Glucose
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Goals

• Provide historical insight on how the diabetics
  metabolism reacts to different foods from
  different places
• Assist in the calculation of carbohydrates by
  allowing for customization of what, where and how
  much was consumed
• Estimate dosage of insulin to inject

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Solution

• Make it easier to calculate carbohydrate intake
• Use formulas to learn individual reactions to
  meals
• Alert the user of possible danger food
• Provide a searchable personal database of foods
• Recommend proper insulin dosage for meals based
  on past history of meal chosen, carbohydrate
  count, and activity level
• Show patterns

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Objectives

• Make life easier
• Take away new founded fear

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Marketing Plan

• Early years
• Emphasis on newly diagnosed diabetics
• Advertising
• Doctor recommendation, Internet ads
• Predicted cost of the product is approximately
  50 dollars
• Client will need PC/PDA or both

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Competition Matrix
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Phase 0 Major Milestones (60 days)?

• Build Website
• Major Functional Component Diagrams
• Feasibility Presentation
• Work Breakdown Structure
• Milestone Presentation
• Funding Agency
• Development Management Plans
• SBIR Presentation

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Management Plan
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Phase 0 Organizational Chart
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Evaluation Plan
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Evaluation Plan

• Phase 0
• Innovative project solution
• SBIR grant application
• Phase 1
• Prototype
• Beta testing
• Market

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Evaluation Plan

• Phase 2
• Functional software
• Successful integration with hardware
• Target Market still obtainable
• Beta testing continues to be successful
• Phase 3
• Breakeven point reached
• eDM gains a satisfactory percent of the target
  market
• Support

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Phase 1 Major Milestones (135 days)?

• Requirements List
• Prototype Test Plan
• Product Prototype User Manuals
• SBIR II Grant Proposal
• Develop Environment Requirements
• Prototype Development Demo
• Test Acceptance Demo
• SBIR Plan
• Update Documentation

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Phase 1 Organizational Chart
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Phase 1 Staff Budget
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Phase 1 Resource Budget
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Phase 1 Prototype Design
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Phase 2 Major Milestones (9 months)?

• Product Specification Review
• Test Plan
• Product User Manuals
• Funding
• Develop Product
• Testing
• Update Documentation

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Phase 2 Organizational Chart
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Phase 2 Staff Budget
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Phase 2 Resource Budget
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Phase 3 Major Milestones (10 years)?

• Assemble Project Team
• Prepare Production
• Procurement Planning
• Requirements
• Solicitation
• Contracting
• eDM Distribution
• Financial Tracking
• Marketing
• Website

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Phase 3 Organizational Chart
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Phase 3 Staff Budget per year
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Phase 3 Resource Budget
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Total Project Costs
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Break Even Analysis
26,486 units must be sold the first year in order
to start making a profit. Estimating 50,000 units
made and sold during year 1. Subsequent years
need only produce enough to offset costs of
production in order to turn a profit.
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Funding Plan

• SBIR Funding Agency National Science Foundation
• Phase 1 100,000
• Phase 2 750,000
• Small business loan
• Phase 3
• Small business loan
• Venture capital investment
• Revenue from sales

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Risk Management Plan

• Identify project risks
• Determine the phase that the risk is in
• Categorize risks according to probability and
  impact
• Reduce risks before or as they happen with
  mitigation actions
• Continue to reevaluate risks during all phases
• Watch for new risks

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Risks Impacts
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Conclusion

• Provide piece of mind
• Regain control of life
• Easier management of
• Insulin distribution
• Carbohydrate calculations

eDM
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QUESTIONS??
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Resources

• Diabetes Health. http//www.diabeteshealth.com/rea
  d/1999/02/01/1409.html
• Medicinenet. http//www.medicinenet.com/diabetes_m
  ellitus
• TechCrunch. http//www.techcrunch.com/2007/08/14/i
  pod-v-the-insulin-pump-adaptive-path-rises-to-the-
  challenge/
• MedlinePlus Medical Encyclopedia.
  http//www.nlm.nih.gov/medlineplus/ency/imagepages
  /19212.htm
• American Diabetes Association - Insulin
  Pumpshttp//www.diabetes.org/type-1-diabetes/insul
  in-pumps.jsp
• Compare Insulin Pumpshttp//www.diabetesnet.com/di
  abetes_technology/insulin_pump_models.php
• Minimed's Paradigm Insulin Pumphttp//www.minimed.
  com/products/insulinpumps/
• Deltec's Cozmore Insulin Pumphttp//www.cozmore.co
  m/default.cfm?CFID6147989CFTOKEN2ffb9fef0b64ead
  7-7FC5ADEE-3048-568B-BEF4AA6CF0A1CE63jsessionidc
  630e562d73b5537803a

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More Resources

• Animas Insulin Pumphttp//www.animascorp.com/
• Insulet's OmniPod Insulin Pumphttp//www.myomnipo
  d.com/products/
• Disetronic's Spirit Insulin Pumphttp//www.roche.
  com/home.html
• http//care.diabetesjournals.org/cgi/content/abstr
  act/dc07-2029v1
• Excellent pump article. http//www.diabetes.ca/Sec
  tion_Membership/DialogueWin00-insulinpump.asp
• Risks. http//www.acmqueue.com/modules.php?nameCo
  ntentpashowpagepid239
• Business Week. http//images.businessweek.com/ss/0
  7/09/0921_diabetes/source/1.htm

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Backup Slides

• DO NOT REMOVE!

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HW Input Output Requirements
Portability
Memory gt X
Display
Keyboard
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Entry Methods
Wireless Transmission Capable
Real Time Monitoring
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Links

• http//www.hoise.com/vmw/04/articles/vmw/LV-VM-06-
  04-16.html
• http//www.lifescan.com/products/otdms/support/otd
  ms_faqmealschedule

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Risk Overview
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Our solution will

• Make it easier to calculate caloric intake
• Use formulas to learn individual reactions to
  meals
• Alert the user of possible danger food
• Provide a searchable personal database of foods
• Recommend proper insulin dosage for meals based
  on past history of meal chosen, caloric count,
  and activity level
• Show caloric patterns

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Our solution will not

• Cure diabetes
• Change existing insulin delivery methods
• Change existing glucose testing methods

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Advantages Of Solution

• Easier to manage glucose levels
• Better understanding of what foods are safe
• Access to historical data categorized into
  activity types

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Disadvantages Of Solution

• Less likely to try foods that the device alerts
  as danger foods
• Expensive if insurance does not cover the device
• May reduce understanding of condition and
  calculations

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Glucose (Blood Sugar) Testing
MedlinePlus Medical Encyclopedia.
http//www.nlm.nih.gov/medlineplus/ency/imagepages
/18029.htm
62
Insulin Injections

• Determine insulin dosage
• Inject Insulin

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Market Analysis per Diabetic Type