Mean Arterial pressure

1
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2
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Mean Arterial pressure
_at_ Pdiastolic 0.33(Psystolic-Pdiastolic)
??? ??? Cardiac Output
??????? ????? ????? Total Peripheral Resistance
X
??? ??? Heart Rate
??? ????? Stroke Volume
X
3
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4
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1. ???? ????? ???? ???? ???? ????? ????
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???????? ??? )Starling Law)
1. ?????? ??????? ???????
Skeletal Muscle Pump .2
3. ??? ???
2. ?????? ??????? ?? ???? ???, ??????? ????????
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5
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???? ??????- ????????? ???????? (????????
????-?????????)
???? ?????? ???- ????? ???????? (????????
???-?????????)
??????? ???????- O2 , NO, Adenosine, CO2, etc
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Mean Arterial Pressure
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Hemorrhage
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-
-
-
-
-

-
Mean Arterial Pressure
-
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Fight or Flight (NA response)
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Mean Arterial Pressure
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Pithed Rat
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????? ??? ???????/????????? "?????"
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12
Dose Response Curves
13
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14
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Real Agonist
Real Antagonist
Physiological Agonist
Physiological Antagonist