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Vitamin E

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How many isomers are possible if there are three chiral centers on Vitamin E. ... a-tocopherol is the only form in vitamin supplements. Think vitamin ... – PowerPoint PPT presentation

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Title: Vitamin E


1
Vitamin E
  • I am not responsible for errors!

2
  • Who showed that that rats maintained on certain
    diets did not produce offspring.
  • Early Viagra

3
  • Evans and Bishop

4
  • What does Tocopherol mean

5
  • Tokas child
  • Phero to bear
  • Ol Alcohol

6
  • How many isomers are possible if there are three
    chiral centers on Vitamin E.

7
  • Eight isomers are possible
  • Chiral centers are
  • 2
  • 4
  • 8

8
  • What are the forms of Vitamin E sold?

9
  • Acetate
  • Hemisuccinate

10
  • What am I?

11
Vitamin E
  • a-Tocopherol Hemisuccinate

12
What am I?
13
  • a-tocopherol acetate

14
  • True or False
  • Vitamin a-tocopherol is the predominant form of
    the vitamin in the US diet?

15
  • False
  • a-tocopherol is the only form in vitamin
    supplements
  • Think vitamin
  • ?-Tocopherol is the predominant form in the US
    diet.
  • Think SO? For natural form

16
  • What is the vehicle Vitamin E travels on in the
    periphery?

17
  • VLDL, LDL, and HDL. It is distributed in adipose
    tissue, liver and muscle.

18
Who am I
19
  • Reduced Tocopherol

20
  • What is one of the few specific nutritional
    deficiencies seen in humans?

21
  • Hemolytic anemia

22
  • What is the RDA of vitamin E?

23
  • 15 mg/day

24
  • True or False
  • ?-Tocopherol is the predominant form in the US
    diet?

25
  • True
  • ?-Tocopherol is the predominant form in the US
    diet.

26
  • In summary, there seems to be a general
    antioxidant role and a specific function in the
    cells__________________.

27
  • In summary, there seems to be a general
    antioxidant role and a specific function in the
    cells oxidation-reduction systems.

28
  • To what extent do we need to know the different
    isomers of vitamin E?

29
  • Not a clue

30
  • Do we need to know the different rankings of d gt
    ? ß gt a?

31
  • So Viagra doesnt work for Dan and he really is
    missing his little buddy. He decides to take
    high levels of vitamin E roughly 300 mg per day.
    Nothing is working right now so he wants to
    increase his consumption to 1200 mg a day. What
    would be the result of taking such high levels of
    Vitamin E.

32
  • Pulmonary Embolism
  • Hypertension
  • Breast Development (Bitch Tits)
  • Severe Fatigue

33
  • What is the potential therapeutic benefit of
    taking vitamin E (old people)

34
  • Possible slowing the progression of Alzheimer's
    disease.

35
  • What is the RDA for Vitamin E again?

36
  • 15 mg/day
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