MR Imaging of Atherosclerosis in Human Carotid Arteries

1
MR Imaging of Atherosclerosis in Human Carotid
Arteries
Chun Yuan, Ph.D. Thomas S. Hatsukami, M.D.
University of Washington
2
MRI of Carotid AtherosclerosisCalcified Plaque

TOF
T1W
T2W
PDW
Exam 7366
3
CE MRI of Carotid Atherosclerosis
Neovasculature and Necrotic Core
10x

Mallorys Trichrome
Pre-Pre Contrast-T1W

25X
Inset (90 rotation)
Post Contrast
Yuan C, et al. JMRI, 1562-67, 2002
4
MRI of Carotid AtherosclerosisReproducibility335
S6
t1
t t1 0
t2
1
t t2 1
t0 t1
t1
t2
t0 t1
DIR T1W T1-T2 2 weeks
t1
t2
Kang et al. MRM, 44968-972, 2000
5
MRI of Atherosclerosis Appearance of
Intraplaque Hemorrhage
10X
?
Movats Trichrome
Yuan C, et al. Circulation, 1042051-2056, 2001.
6
MRI of Atherosclerosis Appearance of Thick
Fibrous Cap
ECA
ECA
ICA
ICA
10X
Ca
Ca
ECA
TOF
PDW
ICA
Ca
ECA
ECA
ICA
ICA
Ca
Ca
T2W
T1W
Yuan C, et al. Circulation, 105181-185 2002.