GOAL NCIDESIGNATION OF STANFORD UNIVERSITY AS A COMPREHENSIVE CANCER CENTER

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GOALNCI-DESIGNATION OF STANFORD UNIVERSITYAS A
COMPREHENSIVE CANCER CENTER

• Email kgblume _at_stanford.edu
• Phone 3-0822
• Fax 8-4418

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NCI-DESIGNATED CANCER CENTERS IN THE USA/CA

• USA CA
• Basic Research Cancer Centers 8
  2
• Clinical Cancer Centers 15
  1
• Comprehensive Cancer Centers 39
  6
• 62 9

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A Comprehensive Cancer Center has reasonable
depth and breadth of research activities in each
of three major areas basic, clinical, and
prevention, control, behavioral and
population-based research and exhibits a strong
body of interactive research that bridges these
scientific areas.In order to receive
recognition as an NCI-designated Comprehensive
Cancer Center the center must meet the above
scientific requirements as well as provide
outreach, education and information on cancer to
the community it serves.
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In the area of clinical cancer research, a
comprehensive cancer center is encouraged to
initiate and conduct early phase, innovative
clinical trials and to participate in the NCIs
cooperative group system by providing leadership
and accruing patients to trials.
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All NCI-designated cancer centers (basic,
clinical or comprehensive) satisfy the following
six characteristics

• 1. CANCER FOCUS
• 2. INSTITUTIONAL COMMITMENT
• 3. CENTER DIRECTOR
• 4. ORGANIZATIONAL CAPABILITIES
• 5. FACILITIES
• 6. INTERDISCIPLINARY COORDINATION AND
  COLLABORATION

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CANCER CENTER SUPPORT GRANT (P30) APPLICATION

• I. Programs in Basic Cancer Research
  Program Leaders
• A. Cancer/Stem Cell Biology Research
  I. Weissman
• B. Genomics Proteomics Research
  P. Brown
• C. Radiation Biology DNA Repair Research
  A. Giaccia
• D. Cancer Biology Cell Cycle Regulation
  Research J. Lipsick
• E. Cancer Immunology Research E.
  Engleman
• F. Cancer Imaging Research
  S. Gambhir
• G. Biomedical Informatics Biomedical
  Computation Research M. Musen
• II. Programs in Translational/Clinical Cancer
  Research
• A. Pediatric Cancer Research Program
  M. Cleary
• B. Lymphoma and Hodgkins Disease
  R. Levy
• C. Hematopoietic Cell Transplantation Biology
  Therapy for Cancer R. Negrin
• D. Genetics of Epithelial Tumors (Skin,
  Breast, GI, GU, GYN) J. Ford
• From Genomic Profiling to Clinical
  Counseling
• E. Cancer Pharmacology/Experimental
  Therapeutics B. Sikic
• III. Program in Population Sciences and
  Education
• A. Cancer Epidemiology/ Cancer Control
  D. West

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CANCER CENTER SUPPORT GRANT (P30)
APPLICATIONResearch Programs

• I. Programs in Basic Cancer Research
• A. Cancer/Stem Cell Biology Research
  I. Weissman, R. Nusse, J. Shizuru, T.
  Cao, M. van de Rijn, G. Harsh, S. Skirboll, T.
  Palmer, V. Tse, S. Kim, N. Teng, A.
  Hussain, L. Giudice, M. Fuller, M. Scott
• B. Genomics Proteomics Research
  P. Brown, G. Nolan, J. Pollack, M. van
  de Rijn, S. Jeffrey, S. So, J. Brooks, P. Utz, G.
  Chu, M. Bogyo, R. Tibshirani,
• V. Pande, T. Hastie, R. Zare
• C. Radiation Biology DNA Repair Research
  A. Giaccia, M. Brown, A. Boyer, L. Xing,
  G. Chu, J. Ford, S. Knox, N. Denko, Q. Le, A.
  Koong, R. Tibshirani, Q. Lu,
• D. Bouley, P. Hanawalt
• D. Cancer Biology Cell Cycle Regulation
  Research J. Lipsick, P.
  Jackson, L. Boxer, D. Felsher, T. Wang, J.
  Axelrod, J. Sage, D. Feldman, M. Powell, S.
  Artandi,
• M. Cleary, J. Crabtree, L. Attardi,
  C. Cartwright, G. Fang, T. Stearns, M. Simon
• E. Cancer Immunology Research E.
  Engleman, M. Davis, R. Levy, E. Butcher, R.
  Negrin, P. Parham, W. Song, A. Krensky, G. Nolan,
  G. Fathman,
• J. Parnes, N. Teng, P. Lee, S.
  Galli, P. Jones
• F. Cancer Cell Tissue Imaging Research
  S. Gambhir, C. Contag, G. Glover, B. Daniel,
  N. Pelc, R. Negrin, S. Plevritis, S. Napel, G.
  Glaser, F. Sommer,
• D. Bouley, D. Nishimura, J. Pauly
• G. Biomedical Informatics M.
  Musen, R. Altman, H. Lowe, R. Tibshirani, R.
  Olshen, N. Risch, S. Plevritis, S. Napel, A.
  Sidow, C. Ball, G. Sherlock,

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Shared Resources (Cores)
LeadersA. Biostatistics for Clinical Cancer
Research R. Tibshirani(Acting), T. LaiB.
Clinical Trials Office B. SikicC. Informatics
Core H. LoweD. General Specialized Animal
Colonies R. Tolvani, M. GarciaE. Cell Tissue
Distribution J. Pollack, J. Norton, D. PeehlF.
High TP DNA Sequencing/SNIP R. Davis, P.
Oefner, R. MyersG. Cancer Imaging C. Contag,
S. Gambhir, B. DanielH. Confocal
Immunoelectron Microscopy S. Smith, J.
MulhollandI. Flow Cytometry G. Nolan, L.
HerzenbergJ. Transgenic and Knock-out Mice M.
Cleary, D. Felsher, Y. Chen.TsaiK. DNA-Micro
Array including Database G. Sherlock, M. Fero,
C. BallL. Proteomics P. Jackson, G.
NolanM. Translational/Clinical Research
Resource G. Fisher
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INVESTIGATORS IN CLINICAL CANCER
RESEARCH/TRANSLATIONAL MEDICINE

• BMT L. Johnston Urology J. Presti
• G. Laport
• R. Lowsky I.R. S. Kee
• K. Stockerl-Goldstein M. Razavi
• M. Stuart D. Sze
• Hematology S. Coutre Radiology R. Birdwell
• P. Greenberg L. Chao
• T. Desser
• Med. Onc. R. Advani G. Glaser
• G. Fisher D. Ikeda
• C. Jacobs B. Jeffrey
• H. Pinto
• S. Srinivas
• Nuc. Med M. Goris
• Rad. Onc. S. Donaldson R. McDougall
• I. Gibbs
• R. Hoppe Pediatrics M. Link
• C. King N. Marina

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External Advisory Board

• M. Abeloff, J. Hopkins
• E. Benz, DFCI
• J. Glick, Penn
• E. Harlow, Harvard
• L. Hartwell, FHCRC
• J. Niederhuber, Wisconsin
• J. Niland, City of Hope
• L. Strong, Anderson
• M. Waldinger, U. Michigan

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TIMELINE FOR CCSG

• February 1, 2003 Start of Planning Process
• March 18, 2003 Dean Pizzo at NCI Meets with NCI
  Director, A. von Eschenbach, M.D.
• April 8, 2003 Faculty Town Hall Meeting re. CCC
• July 24, 2003 Start of National Search for
  Director of CCC/PI of CCSG/Associate
  Director of CSCI
• October 22, 2003 Dean meets with Leaders of
  Programs and Cores
• October 23 and 24, 2003 Visit of first candidate
  for the position of Director
• October 26, 2003 KGB meets NCI Program Director,
  Linda Weiss, Ph.D.
• November 4, 2003 Dean meets NCI Program
  Director, Linda Weiss, Ph.D.
• November 15, 2003 On Campus Retreat of all
  Investigators (BioX)
• January 5 and 6, 2004 Visit of second candidate
  for the position of Director
• March 8 and 9, 2004 Visit of third candidate for
  the position of Director
• March 19, 2004 Review by External Advisory Board
  Members
• April 19, 2004 (t) Dean meets Karen Antman,
  M.D., NCI Director for Cancer Centers
• May 12, 2004 (t) Visit of Linda Weiss, Ph.D. to
  Stanford University
• October 1, 2004 CCSG Application to NCI (Request
  for three years of support)
• January/February 2005 Site Visit by NCI Staff and
  Review Panel Members
• July 1, 2005 Hopefully Begin of NCI Funding

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David Nathan and Edward J. Benz, Jr.

• Comprehensive Cancer Centers and
• the War on Cancer
• Nature, December 2001
• Pages 240-245