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BMC Emergency Medicine Journal Club

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Occult blood in stool can persist for as long as 10d after 250cc PO or 12d after ... Persistence of tarry stool or occult blood doesn't indicate continuation of such ... – PowerPoint PPT presentation

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Title: BMC Emergency Medicine Journal Club


1
BMC Emergency MedicineJournal Club
  • Topic Journal Club About Journal Club
  • July 2008

2
The Origins of Journal Club
  • The biography of Sir James Paget describes a
    regular gathering of self-elect students who
    met in a room over a bakers shop near St.
    Bartholomews Hospital to read journals or play
    cards (1835-1854).

3
The 1st Official Journal Club
  • 1875
  • Sir William Oslers Journal Club in Montreal

4
Journal Clubs Abound
  • Residency training
  • CME
  • Innovative formats and forums

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BMC EM Journal Club
8
BMC EM Journal Club
  • Since 1986 at BCH
  • Joseph Kahn, MD
  • Faithful, conscientious, dedicated steward of the
    written word and defender of evidence-based
    medicine

9
1986 2008
10
1986 2008
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Annals of Emergency Med 1986
16
Annals of Emergency Med 1986
17
Annals of Emergency Med 1986
18
Back to 21st Century
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Todays Agenda
  • History of Journal Club
  • Joseph Kahn Award
  • Publications about Journal Club
  • Brief Review of 4 Articles

21
EM Lit on Journal Club
  • Jouriles NJ. Emergency medicine journal clubs.
    Acad Emerg Med 19963872
  • Burstein J. Enhancing the value of journal club
    use of a structured review instrument. Am J Emerg
    Med 199614561
  • Kuhn GJ. A survey to determine the prevalence and
    characteristics of evidence based medicine in
    emergency medicine residency programs. J Emerg
    Med 200528353.

22
JC about JC
  • Alguire PC A review of journal clubs in
    postgraduate medical education. J Gen Intern Med
    199813347.
  • Objective To summarize elements of successful
    clubs and their effect on postgraduate reading
  • Methods Medline 1966-1997

23
Alguire 1998
  • Conclusions
  • Journal clubs are educationally diverse.
  • Journal clubs with high attendance and longevity
    are characterized by mandatory attendance,
    availability of food, and perceived importance by
    the program director.
  • Studies have failed to demonstrate that
    residents read more or read more critically.

24
Our JClub Goal
  • Studies have failed to demonstrate that
    residents read more or read more critically.
  • To get us all to read more and read more
    critically.

25
JClub Objectives
  • To make us experts in our own literature

26
Article 1
  • Annals of Emerg Med Jun 200851697

27
Byyny 2008
  • Background CT scan technology has evolved since
    original research on CT sensitivity for SAH
  • Objective Are new generation CTs better?
  • Methods Retrospective (2001-2004), single
    institution, all with ICD-9 SAH

28
Byyny 2008
  • Results
  • N149 139 by CT, 10 by LP
  • Overall CT yield 93 (95CI 88-97)
  • Normal MS and HA, CT scan sensitivity was 91
    (95CI 82-97)
  • Conclusion Non-contrast CT exhibits inadequate
    sensitivity to rule out SAH

29
JClub Objectives
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED

30
Byyny 2008
  • Bottom Line Review

31
Byyny 2008
  • Bottom Line Review 3 ½ Joes
  • Lesson Do not ditch the LP

32
JClub Objectives
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED
  • To link primary literature to monthly topic
  • July 2008 Signs and Symptoms

33
Article 2
  • Am J Med Sc 1942 20314

34
Schiff 1942
  • Background It is unknown how well blood in stool
    is associated with ulcer bleeding rate or timing
  • Objective To determine if upper GI blood affects
    blood detection in a patients stool
  • Methods Human volunteers drank 3 week old
    citrated blood mixed with Vichy water to
    disguise the taste

35
Schiff 1942
  • Key Results
  • A tarry stool may result from ingestion of 100cc
    of blood
  • Gross blood and tarry stools may continue for up
    to 8 days after intragastric ingestion of
    1000-2000cc
  • Occult blood in stool can persist for as long as
    10d after 250cc PO or 12d after 2000cc
    intragastric
  • Authors Conclusion Passage of a tarry stool
    doesnt indicate occurrence of severe GI bleed.
    Persistence of tarry stool or occult blood
    doesnt indicate continuation of such GI bleed

36
Victorias Thoughts
  • PART I
  • How much blood gives 1 tarry stool? 100cc
  • Supports conclusion that tarry stool doesnt
    represent severe bleed
  • PART II ??
  • How large of UGI bleed produces BRBPR? Tarry
    stool?
  • Melena or BRBPR doesnt correlate w/ volume of
    blood or location of bleed.
  • PART III
  • Does chemical test represent ongoing bleed?
  • Up to 2 weeks after ingestion- Guaiac

37
Favorite Sentence
  • The designation tarry was applied by us to a
    glistening stool having the same black color as
    found on a standard paint color chart.

38
Victorias Final Word
  • Bottom Line Review 2 ½ Joes

39
JClub Objectives
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED
  • To link primary literature to monthly topic
  • To master new scientific vocabulary
  • Sensitivity, specificity, alpha and beta
    errors, odds ratio, risk ratio, logistic
    regression, confidence interval, Kaplan-Meier,
    kappa statistic, Wilcoxon, Fishers exact, Bayes
    theorum, z-score

40
Article 3
41
McLaughlin 2001
  • Background Lecturalgia (painful lecture) is a
    frequent cause of morbidity for both teachers and
    learners.
  • Objective To devise a schematic for diagnosing
    lecture problems and to provide evidence-based
    recommendations on solving those problems.
  • Methods Lit review ? schematic

42
Key Results
43
Todays Term Lecturalgia
  • Bottom Line Review 2 Joes
  • Lesson Journal club will not be limited to the
    lecture format

44
JClub Objectives
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED
  • To link primary literature to monthly topic
  • To master new scientific vocabulary
  • To inform our own research endeavors

45
Article 4
  • BMJ 2003 32720

46
Smith 2003
  • Background It is assumed parachutes work.
  • Objective To determine if parachutes minimize
    trauma related to gravitational challenge.
  • Methods Systematic review of all
    randomized-controlled trials.

47
Smith 2003
  • Results
  • Search strategy did not find any randomized
    controlled trials of parachute use
  • Authors Conclusion
  • Effectiveness of parachutes has not been
    subjected to rigorous evaluation
  • Only observational data to suggest that
    parachutes reduce morbidity and mortality
  • We need double blind, randomized, placebo
    controlled, crossover trail of parachute use

48
Lauras Thoughts
  • Commentary on EBM which is entertaining and
    thought-provoking
  • Conclusions and proposal are not realistic
  • Good luck with IRB approval
  • Observation data is not always misleading
  • Calcium, Vit D and fracture prevention

49
Favorite Sentence
  • We feel assured that those who advocate
    evidence based medicine and criticize use of
    interventions that lack an evidence will not
    hesitate to demonstrate their commitment by
    volunteering for a double blind, randomised,
    placebo controlled, crossover trial.

50
Another great line
  • Individuals who use parachutes are likely to
    have less psychiatric morbidity and they may also
    differ in key demographic factors, such as income
    and cigarette use. It follows, therefore, that
    the apparent protective effect of parachutes may
    be merely an example of the healthy cohort
    effect.

51
Lauras Final Word
  • Bottom Line Review 4 Joes

52
JClub Objectives
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED
  • To link primary literature to monthly topic
  • To learn new lit-relevant terms
  • To master new scientific vocabulary
  • To remind ourselves daily reading can be fun

53
Next Month
  • Topic Abdomen / GI
  • Residents Kelly Hannigan, EM2
  • Rochelle Lima-Babigian, EM1

54
Summary
  • To make us experts in our own literature
  • To translate Dowling JClub lessons to ED
  • To link primary literature to monthly topic
  • To master new scientific vocabulary
  • To inform our own research endeavors
  • To remind ourselves daily reading can be fun
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