Effect of metoprolol succinate CR/XL vs atenolol on exercise heart rate/SBP over 24 h

1
Effect of metoprolol succinate CR/XL vs atenolol
on exercise heart rate/SBP over 24 h
N 10 healthy men
Systolic BP
Exercise heart rate
160
190
Placebo
Placebo
180
140
Meanexercise SBP (mm Hg)
Meanexercise heart rate (bpm)
170
Atenolol 50 mg
120
Atenolol 50 mg
160
Metoprolol succinate CR/XL 100 mg
Metoprolol succinate CR/XL 100 mg
100
150
0
0
0
2
8
12
24
4
0
2
8
12
24
4
Time (hours)
Time (hours)
Blomqvist I et al. Eur J Clin Pharmacol.
198833(suppl)S19-24.