False Discovery Rate for Shape Analysis: Develop algorithm and ITK software module for False Discovery Rate (FDR) analysis.

1
False Discovery Rate for Shape AnalysisDevelop
algorithm and ITK software module for False
Discovery Rate (FDR) analysis.
2006 Summer PrWeek
Plan/Expected Challenges/Publication
Team
Algorithms False Discovery Rate(FDR) for local
shape analysis.
Martin Styner, UNC (algorithms) Jim Miller, GE
Research (software support) Jim Levitt, VA
Brockton, Harvard (clinical data)
Software Convert current non-ITK statistical
analysis to ITK-compatible classes for current
method. Add new implementation for FDR
Clinical Comparison to current results on male
SPD caudate study.
Expected Date for Insight Journal Publication
Submission to MICCAI open source workshop during
project week or one week after that.
Accomplished by end of Programming Week
Raw

• New Software classes for FDR
• Testing on male SPD caudate data
• Less conservative then permutation test based
  correction
• Dissemination to BWH for other studies
• Insight Journal publication MICCAI 2006

FDR
PermTest
M Styner, I Oguz, S Xu, C Brechbuhler, D
Pantazis, J Levitt, M Shenton, G GerigFramework
for the Statistical Shape Analysis of Brain
Structures using SPHARM-PDM, Open Science
Workshop at MICCAI 2006, Insight Journal
http//hdl.handle.net/1926/215