Multiple Sequence Alignment Case Studies

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Multiple Sequence Alignment Case Studies

• Workshop on Creating Bioinformatics Programs
• Pittsburgh Supercomputing Center
• July 19, 2006
• Hugh B. Nicholas Jr.
• nicholas_at_psc.edu

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MSA alignment of 20 phospholipases A2
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MSA
MSA - Hand
Saga
Clustal W
ProbCons
T-Coffee
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T-Coffee
MSA
Clustal W
ProbCons
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T-Coffee
MSA
Clustal W
ProbCons
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ProbCons
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Six Aspartyl Proteases Aligned by MSA
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Six Aspartyl Proteases Aligned by MSA
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Clustal W
ProbCons
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Aspartyl Protease Structures
Gly 78
Gly 80
Gly 81
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Aspartyl Protease Structures
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14 Cytrochrome Cs Aligned by MSA
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14 Cytochromes C MEME ZOOPS motifs
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14 Cytochromes C MEME OOPS motifs
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Unedited ClustalW Alignment
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Unedited ClustalW MEME
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First Edit - ClustalW MEME
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Second Edit ClustalW MEME
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Fully Edited ClustalW MEME
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Fully Edited ClustalW Conservation
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MSA Alignment
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T-Coffee Alignment - Conservation
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Probcons Alignment - Conservation
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T-Coffee Alignment MEME Patterns
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Probcons Alignment MEME Patterns