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A Flavour of Errors in Variables Modelling

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We have two variables, ? and ?. ? and ? are linearly related ... Down's Syndrome. Affects 1 in 1000 children born in the UK. Down's is caused by the presence of ... – PowerPoint PPT presentation

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Title: A Flavour of Errors in Variables Modelling


1
A Flavour of Errors in Variables Modelling
  • Jonathan Gillard
  • GillardJW_at_Cardiff.ac.uk

2
Constructing the Model
  • We have two variables, ? and ?.
  • ? and ? are linearly related in the form ? aß?.
  • Instead of observing n pairs (?i, ?i) we observe
    the n data pairs (xi,yi), where
  • xi ?i di
  • yi ?i ei
  • and it is assumed that ?i and ?i are independent
    error terms having zero mean and variances sd and
    se respectively.

2
2
3
Downs Syndrome
  • Affects 1 in 1000 children born in the UK.
  • Downs is caused by the presence of an extra
    chromosome. An extra copy of chromosome 21 is
    included when the sperm and the egg combine to
    form the embryo.
  • Screening tests are used to calculate the chance
    of a baby having the condition.

4
The Data Set
5
How can we fit a line?
  • There are clearly errors in both variables.
  • To use standard statistical techniques of
    estimation to estimate ß, one needs additional
    information about the variance of the estimators
    Madansky (1959)
  • We know the dating error is 2 days this is
    enough information!

6
Method of Moments
  • The method of moments has a long history,
    involves an enormous amount of literature, has
    been through periods of severe turmoil associated
    with its sampling properties compared to other
    estimation procedures, yet survives as an
    effective tool, easily implemented and of wide
    generality
  • Bowman and Shenton

7
Method of Moments
  • The maximum likelihood approach to estimation is
    primarily justified by asymptotic (as the sample
    size goes to infinity) considerations
  • Cheng and Van Ness

8
Estimating the Parameters
  • As the dating error is 2 days, then sd 2.
  • Use a modified y on x regression estimator ß
    sxy / (sxx - sd).
  • Other parameters i.e. intercept a can be
    estimated from the method of moment equations.

2
9
Regression Lines
10
Typology of Residuals
  • What are residuals used for?
  • Prediction
  • Model checking
  • Leverage
  • Influence
  • Deletion

11
Estimating the true points
  • Two naive m.m.es of ?
  • The optimal linear combination is

12
The Estimated True Points
13
Estimated true against observed
14
A residual?
  • Attempt to write as a usual regression model
  • y a ßx (e - ßd)
  • 1. x is always random due to random error
  • 2. Cov(x, e ßd) -ßsd
  • 3. Using ordinary l.s. estimates leads to
    inconsistent estimators

2
15
Residuals
16
Residuals again!
17
  • Questions?
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