Subdermal Electrocorticography Telemitter for Human Patients with Epilepsy

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Subdermal Electrocorticography Telemitter for
Human Patients with Epilepsy
March 17, 2003

• Group 1
• Presenter Alex Chieu
• Partners Byron Kam Matt LaConte
• Mentor Dr. Dan Moran
• Advisor Dr. Eric Leuthardt

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Background

• 2 million people affected with Epilepsy in U.S.
• Often unsure of location of the brain that causes
  it
• Must analyze brain to find cause

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Background
Current Method AD-Tech Sensor Array
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Current Problems

• External Wires
• Leaking Spinal Fluid
• Infection - Bacteria able to travel through holes
  in skin
• 25 Likelihood
• Antibiotics 1,000/day
• 2 extra surgeries 10,000/each
• ICU 1,500/day
• Total Cost 50,000

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Current Problems (Contd)

• Lack of Mobility
• Hardwired to Computer
• Bedsores
• Low Patient Compliance

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Design Requirements

• Fully contained under closed scalp
• Reduce the rate of infection to that of closed
  head procedures 1
• Must supply physicians with 2 weeks of sensor
  information
• Increase patient comfort, well-being, mobility

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Design Requirements (Contd)

• Fully compatible with current technology/devices/m
  ethods
• Cost 1,500
• User friendly
• Easily implantable
• Sterilizable

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Specifications

• Distance of transmission 5 cm - 10 m
• Sampling frequency 100 Hz
• Transmission frequency 1.4 GHz - 1.7 GHz
• Data Continuous transmission of raw data for up
  to 14 days
• Sensor Range .05 - 1 mV
• Output 50 - 1000 mV
• Resolution gt 12-bit
• Thickness lt 1 cm

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Design Breakdown

• Telemetry
• Power Source
• Packaging Form Factor

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Data Transmission Options

• Data Recorder
• Wireless Telemetry
• Radio Frequency (RF)
• Bluetooth
• Cellular
• AM/FM
• Optical Transmission
• UV
• IR
• Visible
• Sonics

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Analysis of Data Transmission
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Analysis of Data Transmission
Radio Frequency
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Analysis of Data Transmission
Optical
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Analysis of Data Transmission
Miscellaneous Methods
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Power Source Alternatives

• Battery
• Battery/Inductive Charging Combo.
• Inductively Powered
• Similar to Bion Neurostimulators

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Analysis of Power Sources
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Form Factors

• Attachment of Device
• Scalp
• Skull
• Free-floating
• Single Hockey Puck
• Multiple Hockey Puck
• Beveled Plate
• Integrated Island Design
• Stick of gum Design

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Stick of Gum Design
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(No Transcript)
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Analysis of Form Factors
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Our Design (in a nutshell)

• Transmitter Bluetooth
• Power Source Battery/Inductive Charging
  Combination
• Form Factor Stick of Gum Design

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Materials

• Bluetooth Telemitter and DSP
• Flexible Silicon-based mold
• 12-bit Analog to Digital Converter
• 50 Hz Low Pass Filter
• 16-channel Multiplexor
• 1000x Pre-amplifier
• Battery/Charging Combo

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Manufacturing

• AD-Tech Sensor Arrays
• Vishay A/D Conversion
• Analog Devices Pre-amp, multiplexor, LPF
• Siemens Bluetooth Module
• Power Source Bion
• Assembled and hermetically sealed by AD-Tech
  Medical

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Organization of Responsibilities

• Byron Kam
• Web Developer
• Expert in Methods of Transmission
• Electrical Engineer
• Matt LaConte
• Patent Searches
• Contacting Vendors
• Mechanical Engineer
• Research Circuit Components
• Alex Chieu
• Literature Searches
• Researching Power Supplies
• Electrical Engineer

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Design Schedule
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Acknowledgements

• Dr. Dan Moran
• Mentor
• Dr. Eric Leuthardt
• Neurosurgery Advisor/Expert
• Dr. Klaesner
• Design Professor