Biomedical Informatics: use of information technology and advanced research computing in the practice of biomedical sciences and medicine

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Biomedical Informaticsuse of information
technology and advanced research computing in the
practice of biomedical sciences and medicine
(wikipedia)

• Joel Saltz MD, PhD
• Chair Department of Biomedical Informatics
• The Ohio State University College of Medicine

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Transcontinental Railway The Golden Spike -
Triumph of Standards
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Major Break-of-GaugeTransiberian, Manchurian
Railroad

• Cant always standardize
• Optimize transfer
• Adapt trains
• Move cargo
• Time consuming, expensive
• Can be automated

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Translation Same ideas, different words
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Biomedical Informatics and Middleware
Translates and Integrates Information
Disseminates Information
Brings in Information
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caBIG Application community led effort

• caGrid octopus for caBIG
• OSU-led project
• Ohio State/Rescentris Bioinformatics BRTT laid
  groundwork

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caGrid

• Grid Infrastructure for caBIG
• caGrid Components
• Grid Service Graphical Development Toolkit
  (Introduce)
• Metadata
• Advertisement and Discovery
• Semantic Services
• Workflow
• Security

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caGrid 1.0 Security

• Authentication
• Process of determining whether someone or
  something is, in fact, who or what it is declared
  to be.
• http//en.wikipedia.org/wiki/Authentication
• Authorization
• Process of determining if an authenticated user
  may do something on a given resource.
• Can User X perform Operation Y on Resource Z?
• http//en.wikipedia.org/wiki/Authorization

• Trust Management
• Supports applications and services in deciding
  whether or not signers of digital
  credentials/user attributes can be trusted.
• Secure Communication
• The ability to guarantee the integrity and/or
  privacy of messages between two parties

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System Architecture - Virtual PACS
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GridIMAGE

• Query heterogeneous set of DICOM, SQL or caGrid
  data services
• Select images based on search criteria
• Send images to human reviewer
• Send images to algorithm for CAD or change
  detection

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Ongoing Testbed Cooperative Group Collaborations

• ACRIN
• QARC
• ATC
• RTOG
• CALGB
• COG
• NCIA

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Middleware High Resolution 3-D Tissue
Reconstruction
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Woody Hayes Success - it's what you do with
what you've got.
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Thanks!
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caGrid Team

• Ohio State University - Department of BioMedical
  Informatics (http//bmi.osu.edu/)
• Dave Ervin
• Shannon Hastings
• Tahsin Kurc
• Stephen Langella
• Scott Oster
• Joel Saltz
• Argonne National Lab / University of
  Chicago(http//www.globus.org)
• William Allcock
• Jarek Gawor
• Ravi Madduri
• Frank Siebenlist
• Michael Wilde

• Duke University
• A. Jamie Cuticchia
• Patrick McConnell
• Georgetown University
• Colin Freas
• Paul A. Kennedy
• Chad La Joie
• SAIC (http//www.saic.com)
• Manav Kher
• Booz Allen Hamilton (http//www.bah.com)
• Arumani Manisundaram
• Michael Keller
• Reechik Chatterjee

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gridCAD Team

• Tony Pan, Joel Saltz, Tahsin Kurc, Stephen
  Langella,
• Shannon Hastings, Scott Oster, Ashish Sharma,
  Metin Gurcan
• Department of Biomedical Informatics
• The Ohio State University Medical Center,
  Columbus OH
• Eliot Siegel, Khan M. Siddiqui
• University of Maryland School of Medicine,
  Baltimore, MD

For more information, please contact Tony Pan
(tpan_at_bmi.osu.edu) Dept. of Biomedical
Informatics, The Ohio State University
http//bmi.osu.edu
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Microscopy Image Analysis

• Human Cancer Genetics
• Pamela Wenzel
• Dr. Gustavo Leone
• Dr. Alain deBruin
• Dr. Tony Trimboli
• Jana Opavska

• Biomedical Informatics
• Tony Pan
• Alexandra Gulacy
• Dr. Metin Gurcan
• Dr. Ashish Sharma
• Dr. Kun Huang
• Dr. Joel Saltz
• Computer Science and Engineering
• Raghu Machiraju
• Kishore Mosaliganti
• Randall Ridgway
• Richard Sharp