MLH1/MSH2 Mutation Prevalence

1
MLH1/MSH2 Mutation Prevalence
Family History (Includes at least one first or second degree relative) Family History (Includes at least one first or second degree relative)
Personal History No Affected Relatives gt1 Relative Affected
Colorectal Cancer lt50 9.1 22
Colorectal Cancer gt50 lt5 15
Endometrial Cancer lt50 11 23
Other HNPCC Cancer 6.5 16
gt1 HNPCC Cancer Not available 36
N1434 Estimate calculated according to PREMM12
model Myriads Nlt50. PREMM12 model can be found
at http//www.dana-farber.org/pat/cancer/gastroin
testinal/crc-calculator/default.asp
www.myriadtests.com