Cervical cancer

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Cervical cancer

• Mike Brown

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Epidemiology

• 1 in 200 women in Australia by age 75
• 14th most common cancer
• Mean age 47years
• Indigenous women 10 times higher rate
• Number one killer of Indigenous women
• 75 percent decrease in the incidence of cervical
  cancer over the past 50 years in developed
  countries

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Epidemiology
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Epidemiology
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Epidemiology
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Risk Factors

• Smoking - 4 times increase
• Sexually active from a young age

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Risk Factors
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Aetiology

• Helicobacter Pylori
• Found in 70 - 90 patients with PUD
• NSAID
• Stress ulcers in critically ill patients

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Pathogenesis

• Normal Mucosa

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Pathogenesis

• Ulcer formation
• Picture of mucosa with ulcer, erosion to blood
  vessel and perforation

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References

• Cancer Research UK
• http//publications.cancerresearchuk.org
• National Cervical Screening Program
• http//www.cancerscreening.gov.au/internet/screeni
  ng/publishing.nsf/Content/facts
• Spence, AR, Goggin, P, Franco, EL. Process of
  care failures in invasive cervical cancer
  systematic review and meta-analysis. Prev Med
  2007 4593.