Cross%20Coupling%20Reaction

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Cross Coupling Reaction
1) Stille Reaction 2) Suzuki Reaction 3)
Sonogashira Reaction
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Carbonylative Cross Coupling Reaction
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1) Stille coupling ??
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Intramolecular Stille Reaction
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Recycle of Sn
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2) Suzuki coupling Reaction
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Intramolecular Suzuki Reaction
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Synthesis of Bombyokol
Aromatic boronic acid
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Unreactive Compounds
Reactivity of Halide vinyl iodide, vinyl
bromidearyl iodide gt vinylchloride aryl
bromide, Reactivity of Catalysts PdCl2(PPh3)2,
Pd(PPh3)4, Pd(OAc)2, PdCl2
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3) Sonogashira coupling
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Anticancer nucloside
Metal acetylide Sn, Zn, Mg
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Wacker Process
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Historically, in 1894 Phillips reported that
acetaldehyde and Pd(0) was isolated from
ethylene gas and aqueous PdCl2. This was
further developed by using CuCl2 and O2.
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