From the iCAPTURer to McManusInformaticus

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From the iCAPTURer to McManus-Informaticus

• Benjamin Good
• Wilkinson Laboratory
• iCAPTURE Centre, UBC

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A Brief History of Ben

• 1998 BS, UC San Diego,
• Cognitive Science
• 1999 Knowledge Engineer, SAIC
• 2000 MSc Sussex Uni., UK,
• Evolutionary and Adaptive Systems
• (clever computer programs)
• 00-03 Bioinformatician, UCSD, CFAR
• now - PhD student, Bioinformatics Training
  Programme

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Knowledge Based Systems

• Software systems that contain representations of
  human knowledge and can thus emulate human
  behaviour (to some extent).

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Knowledge Based Systemsin practice

• 1997 IBM computer program Deep Blue defeats world
  chess champion

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BHAG

• McManus-Informaticus
• Deep Blue for Biomedical Research.
• What are the Biomarkers of allograft rejection
  likely to be?
• Hypothesis generation
• Hypothesis validation

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Knowledge Representation
Is hard and takes a lot of time
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Neurosurgery?
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The iCAPTURer
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First Trial at YI Forum

• 2 days to build the YI Ontology
• 68 volunteers
• 665 terms collected
• 326 is a kind of relations collected
• 340 same as relations collected
• Quality assessment underway
• Manuscript in preparation

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Thanks to Dr. McManus

• For hiring Dr. Mark Wilkinson
• For suggesting I go to the YI Forum
• For introducing me to the term BHAG
• For posing in one of my most frequently used
  slides
• And for sending me this in an email
• thanks especially for pushing boundaries.