Virology and HIV

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Virology and HIV

• Lecture 7
• Introduction to viruses (II)
• Life Cycle of HIV-1 (I)

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Viruses

• Virus particles consist of
• Genetic material
• A system for protecting the genetic material and
  introducing it into a cell

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How does a virus Infect a Host?
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Virus Infection Cycle

• Adsorption
• Penetration
• Expression of the viral genetic material
• Organization of the infected cell for virus
  expression
• Replication of the viral genetic material
• Synthesis of proteins for viral particles
• Assembly of virus particles an release

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The Life Cycle of a Retrovirus

• Steps in Formation of ds-DNA from Retroviral
  ss-RNA

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The structure of Retrovirus

• Gag
• Pol
• Env

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