PCRN SW East Hub

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PCRN SW East Hub

• Dr Jenny Baverstock, East Hub Manager

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Regional coverage
Based at Primary Medical Care University of
Southampton
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Organisation
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• Two sore throat studies
• Both have a web based clinical data collection
  form
• DESCARTE MRC study recruiting 18,000 patients
  with sore throat documenting presenting symptoms.
  
• Comparing those patients who recover with those
  who develop complications will reveal specific
  symptoms which are associated with serious
  outcome.
• Currently recruiting throughout the SW region
  (Poster)
• PRISM A DH funded study investigating the
  effectiveness of Streptococcal rapid testing kits
  compared to symptom evaluation or delayed
  prescription in targeting antibiotic use in
  patients with sore throat.

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DeNDRoN 007

• AZ study adopted on the UKCRN portfolio,
  currently led by DeNDRoN
• This study will be recruiting dementia patients
  and their carers in both primary care and
  secondary care. The aim is to provide information
  on carer burden in dementia via a questionnaire
  and also assessment of the severity of dementia
  as assessed by MMSE. The study will be recruiting
  20 pairs in the East Hub region.
• 7 practices have expressed an interest in
  recruiting for this study

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HEAT

• Developmental MRC pilot trial designing a study
  to assess whether eradicating H. pylori in
  patients taking low dose aspirin reduces
  gastrointestinal bleeding.
• First step assessing the prevalence of aspirin
  use and of H. pylori infection in aspirin users,
  the success of eradication treatment and the
  acceptability of breath testing and eradication
  to patients.

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Studies currently put forward for adoption

• GRACE (EU)
• Programme of research into cough and chest
  infections in 10 EU countries
• Two parts RCT assessing the effect of
  amoxycillin or placebo in altering symptom
  duration and severity in acute LRTI.
  Observational study those presenting with LRTI,
  variables will be identified that predict
  prognosis.
• GLOW
• Funded by an educational trust recruiting 42000
  women over 55 from 9 countries
• Surveying annual data regarding osteoporosis risk
  and management over 5 years

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Ways of working with primary care

• Register of interested practices (50) now
  expanding to other professions
• Register lists interests for targeted approach
• RO visiting practices
• Support for recruitment
• Newsletter
• Direct contact
• Assistance with database searches
• Additional support for trial can be provided with
  network reimbursed for study support from study
  resource
• Service support costs from CLRN

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Contact information

• Jenny Baverstock
• Aldermoor Health Centre
• Aldermoor Close
• Southampton
• SO16 5ST
• 02380241055
• www.pcrnsw.org
• Email pcrnsw_at_soton.ac.uk
• Jenny_at_soton.ac.uk
• See leaflet for other contact details