Clinical effectiveness of Influenza Vaccine - Dr Sheetu Singh Chest Specialist

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Have we made any progress towards Prevention?

• Multisite Influenza surveillance Network
  Improved Influenza Detection

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10 cities data suggests 14 of the total samples
sent were Influenza positive
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A(H1N1) in India, 2009-15
Time period May 2009-Dec 2009 Jan 2010-Dec 2010 Jan 2011-Dec 2011 Jan 2012-Dec 2012 Jan 2013-Dec 2013 Jan 2014-Dec 2014 Jan 2015-Feb 2015
Cases 27236 20604 603 5044 5253 937 18,105
Deaths 981 1763 75 405 699 238 1,005
Mortality ratio 3.60 8.55 12.44 8.03 13.31 25.40 5.75

• Not everyone that dies with an influenza-like
  illness is tested for influenza
• Influenza-associated deaths are often a result of
  complications secondary to underlying medical
  problems, which may be missed.

Are we Seeing Tip of the Iceberg?

• Data till February 27, 2015 (Source Office of
  the Director, Emergency Medical Relief,
  Directorate General of Health Services,
  Government of India, New Delhi.)
  https//flutrackers.com/forum/forum/india/seasonal
  -flu-2009-2014-including-h1n1-pandemic-2009-ai/721
  670-india-influenza-2015-2-868-media-reported-fata
  lities/page6
• http//www.japi.org/april_2015/08_ua_h1n1_revisite
  d_after_six.html

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What do we understand?

• With very limited data theres enough reason to
  believe that the magnitude of the problem is much
  higher in developing countries including India as
  compared to the developed countries

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Clinical effectiveness of Influenza Vaccine