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Mabtas is a anticancer medicine which prevents the growth and spread of cancer cells in the body – PowerPoint PPT presentation

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Title: helenachristy


1
MILLION HEALTH PHARMACEUTICALS
  • Mabtas 100mg - Anticancer drugs view uses, side
    effects and price MHP

2
DESCRIPTION
  • Mabtas 100mg is a anticancer medicine which
    prevents the growth and spread of cancer cells in
    the body. 
  • Mabtas 100mg injection also indicated for the
    treatment of Non- Hodgkins lymphoma or chronic
    lymphocytic and with combination with another
    anticancer drugs like methotrexate is used for
    rheumatoid arthritis symptoms in adult
    treatment. 
  • Mabtas 100mg with steroid regimen combination is
    given for the treatment of some rare disorders
    which cause blood vessels and other tissues
    inflammation in the body.

3
INDICATION
  • Mabtas 100mg injection and hyaluronidase human
    injection are given alone or combination with
    another drugs to treat certain types of
    non-Hodgkin's lymphoma and chronic lymphocytic
    leukemia (cancer start in WBC). 
  • Mabtas 100mg injection is also used with
    methotrexate (Otrexup, Rasuvo, Xatmep, others)
    for the treatment rheumatoid arthritis symptoms
    in adults that have been already treated with a
    some type of regimen known as tumor necrosis
    factor (TNF) inhibitor. Mabtas 100mg is a type in
    a classification of drugs called monoclonal
    antibodies.

4
NON HODGKINS LYMPHOMA
5
PHARMACODYNAMIC
  • new type of "targeted" cancer treatment and an
    integral part of the body's immune system.
    Naturally the body build antibodies in along with
    to an antigen which has entered the body and
    attach to the antigen for destruction by the
    immune system. An essential cells only aimed by
    monoclonal antibiotics, they may leads to less
    toxicity to healthy cell and it is usually
    treatment recommended only for cancers in which
    antigens (and the respective antibodies) have
    been already identified. Mabtas works by linking
    to the CD20 antigen on normal and malignant
    B-cells. Hence the body's essential immune
    security are initiated to attack and kill the
    marked B-cells. Stem cells i.eyoung cells in the
    bone marrow which will grow into the various cell
    types and do not have the CD20 antigen. After
    treatment,CD20 antigen allows healthy B-cells to
    multiply

6
PRODUCT DETAILS
  • Brand MabtasIngredients Rituximab Strength
    100mg Manufactured Intas pharmaceuticalsPack
    age injection

7
PHARMACOKINETICS
  • ABSORPTIONNot availableDISTRIBUTIONvolume of
    distribution is 3.1 LMETABOLISMMabtas 100mg
    injection metabolized by human antimurine
    antibody production.EXCRETIONnot available The
    half life of NHL is 22 days and for RA is 18.0
    days, GPA and microscopic polyangitis is 23 days

8
DOSAGE MANAGEMENT
  • Mabtas 100mg is recommended to administer only
    through intravenous infusion not by IV push or
    bolus.
  • ADMINISTRATIONTake an Mabtas 100 mg
    injection amount and diluted to final
    concentration of 1 mg/ml upto 4 mg/ml as infusion
    (containing either 0.9 Nacl or 5 dextrose in
    water). Invert gently the bag and mix the
    solution. Dispose unused drug left in vial. 
  • OVERDOSAGE If the patients had high dose
    of Mabtas 100mg then seek immediately to the
    emergency department or poison control help line.
    Please consult the doctor for further
    clarification.

9
PRECAUTIONS
  • Allgeric condition against Mabtas 100mg or any
    other medication informs your doctorWhile
    using Mabtas 100mg injection do not take any
    vaccination or immunization without taking advice
    from doctors. Avoid use of Mabtas 100mg if you
    are pregnant. It will harm the baby unborn, while
    using 
  • Mabtas 100mg use correct birth control to prevent
    pregnancy and for at least 2 weeks after your
    treatment ends. 
  • Mabtas 100mg injection may affect the ability to
    have children in women.

10
SIDE EFFECTS
  • COMMON EFFECTS
  • fever and chills (flu lik symptoms)LESS COMMON
    SIDE EFFECTS
  • Weakness nausea headache cough dyspnae
    pharyngitis

11
DRUG INTERACTION
  • Mabtas 100mg drug interaction has limited data is
    available at present. Combination with
    fludarabine or cyclophosphamide has no effects in
    pharmacokinetics in CLL patients. Combination
    with methotrexate had no effects in
    pharmacokinetics.

12
CONTRAINDICATIONS
  • Hypersensitivity or murine proteins. Active
    severe infectons in rheumatoid arthritis
    Uncontrolled cardiac disease.

13
PREGNANCY
  • CategoryC animal studies reproduction shown an
    adverse effect on the fetus. The drug has no
    sufficient and well controlled studies in humans,
    using in pregnant women benefits by warrant use
    of the drug.

14
LACTATION
  • Mabtas 100mg injection excreted into human milk
    is unknown. Due to the drug belongs to large
    protein molecule, no information is available.
    Women should not breast feed during Mabtas
    100mg treatment and 12 months following last dose.

15
STORAGE
  • Store at 2C 3CUse the drug before expiry
    dateProtected from direct sunlightDo not freeze
    or shake.Keep away from the childernsDiscard
    the unused drug by asking the advice from doctor
    or pharmacist.

16
MISSED DOSE
  • Store at 2C 3CUse the drug before expiry
    dateProtected from direct sunlightDo not freeze
    or shake.Keep away from the childernsDiscard
    the unused drug by asking the advice from doctor
    or pharmacist.

17
CONTACT US
  • EMAIL ID
  • millionhealthpharmaceuticals_at_gmail.com
  • PHONE NO
  • 91-9940472902
  • WEBSITE URL https//millionpharma.com/mabt
    as-100mg.php
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