Can Entecavir lower the risk of Hepatocellular carcinoma in Hepatitis C patients

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Can Entecavir Lower the Risk of Hepatocellular
Carcinoma in Hepatitis C Patients
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Hepatocellular Carcinoma or HCC is the commonly
diagnosed form of liver cancer. It is most
likely to occur in people with a chronic liver
disease such as hepatitis C infection.
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Hepatitis C virus or HCV is a major contributing
factor towards cirrhosis and advanced hepatic
fibrosis and increased risk for the development
of HCC. The mortality rates of HCV associated
HCC remain consistently high as the rates of HCV
cirrhosis also increase.
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The usage of new directly acting anti-viral
medications (with higher rate of virological
clearance) have great potential as a cure for HCV
infections. While the HCC-HCV correlation is
reduced due to such medications such as
Enteacavir.
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The patients treated with Entecavir / Baraclude
remain at risk of developing HCC, especially in
case of patients with cirrhosis and advanced
fibrosis. Entecavir / Baraclude price
information
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Entecavir (Brand Baraclude) along with another
medication Tenofovir (Brand Telura, Vired) are
the most commonly prescribed anti-viral
medications for the first-line treatment of
Hepatitis C virus. Entecavir and Tenofovir have
similar efficacies in virologic responses and are
thus equally recommended by doctors. Their
association with the development of
hepatocellular carcinoma is unclear.
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Clinical Trial for Entecavir A nationwide
clinical study in Korea was conducted to observe
the risk of developing HCC, liver-related
mortalities and risk of liver transplant due to
treatment with Entecavir and Tenofovir. The
study involved patients who were either being
treated with Entecavir / Baraclude or Tenofovir /
Viread. The timeline of the study was 2 years
from 1st January, 2012 to 31st December, 2014.
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The objective of this study was to learn the
cumulative transplant, death and HCC
rates. Results The groups were evenly matched
in respect to the fact that mean ages of patients
treated with Entecavir and Tenofovir were 48.6
years 49.3 years.
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26.1 of the patients who were being treated with
Entecavir had cirrhosis. While, 27.5 of the
patients who were being treated with Tenofovir
had cirrhosis. The rates of viral DNA
suppression and liver enzyme normalization for
both Entecavir and Tenofovir were also similar.
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• The conclusion of the study suggests that
  Entecavir may be less effective decreasing the
  risk for HCC, or reducing the risk of needing a
  liver transplant and of liver-related death.
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• Entecavir side effects
• Some side effects from taking Entecavir include
• Pain in muscles
• Light headedness
• Difficulty in breathing
• Inconsistent heart rates
• Pain in stomach
• Nausea and/or vomiting
• Numbness in limbs

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• Some of the more common side effects include
  dizziness, headache, tiredness and nausea.
• Entecavir Dose
• Entecavir / Baraclude generally is available in
  the following doses
• Enticavir Generic 0.5 mg Tablets
• Enticavir Generic 1 mg Tablets
• Brand Baraclude 0.5 mg Tablets
• Brand Baraclude 0.5 mg/ml Oral Solution
• Brand Baraclude 1mg Tablets

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Entecavir cost information The information
provided on the page is meant for the purpose of
being helpful and educational. It should not be
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