Baculovirus-Insect Cell Expression

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Baculovirus-Insect Cell Expression
Creative BioMart
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The baculovirus cell expression system utilizes
recombinant baculoviruses (insect viruses) and
their ability to manufacture high yields of
biologically active proteins from infected insect
cells. The proteins of interest can be easily
purified from infected cells or their
supernatants using tag and affinity
chromatography.
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At Creative BioMart, our team of experts have
developed baculovirus-insect cell expression
platform for virus production and recombinant
protein manufacture in various scales. The
ability of Creative BioMarts baculovirus-insect
cell system to express proteins with complex
post-translational modifications (PTMs),
combining with high production yield, makes it
perfectly suitable for generating mammalian
proteins, especially cellular signaling proteins
including protein kinases, protein phosphatases
and cellular protein substrates, amongst others.
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In order to adapt to different purposes of our
customers, Creative BioMart offers various
approaches to generate a recombinant baculovirus
system containing the gene of interest.
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Advantages of working with Baculovirus-Insect
Cell Expression System
Improved solubility Able to perform complex
PTMs High protein expression levels compared to
other higher eukaryotes Suitable for the
production of large proteins and protein
complexes Capable of producing cytotoxic
proteins Easy to scale up in bioreactors Lower-cos
t Operational safety baculovirus are
noninfectious to vertebrates.
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